Figures and Tables : Initial sequencing and comparative analysis of the mouse genome : Nature

From the following article:

Initial sequencing and comparative analysis of the mouse genome

and Mouse Genome Sequencing Consortium

Nature 420, 520-562(5 December 2002)

doi:10.1038/nature01262

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Figure 1

The mouse genome in 88 sequence-based ultracontigs.

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Figure 2

Conservation of synteny between human and mouse.

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Figure 3

Segments and blocks >300 kb in size with conserved synteny in human are superimposed on the mouse genome.

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Figure 4

Dot plots of conserved syntenic segments in three human and three mouse chromosomes.

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Figure 5

Size distribution of segments and blocks with synteny conserved between mouse and human.

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Figure 6

Size ratio of mouse to human for orthologous 100-kb windows.

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Figure 7

Distribution of (G+C) content in the mouse (blue) and human (red) genomes.

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Figure 8

(G+C) content and density of CpG islands shows more variability in human (red) than mouse (blue) chromosomes.

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Figure 9

Comparison of (G+C) and gene content in mouse and human.

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Figure 10

Age distribution of interspersed repeats in the mouse and human genomes.

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Figure 11

Density of interspersed repeat classes at different (G+C) content in the mouse (a) and human (b) genomes.

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Figure 12

Conservation of (G+C) content and convergence of interspersed repeat distribution between the human and mouse genomes.

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Figure 13

Correlation of order-specific SINEs and LINEs in human and mouse orthologous regions.

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Figure 14

The zinc-finger homeobox 1b (Zfhx1b) loci in human and mouse are both repeat poor.

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Figure 15

Comparison of L1 characteristics of autosomes and sex chromosomes as a function of (G+C) content in mouse (blue) and human (red).

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Figure 16

Structure of a new homologue of dystrophin as predicted on mouse chromosome 1 and human chromosome 2.

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Figure 17

Taxonomic breakdown of homologues of mouse proteins according to taxonomic range.

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Figure 18

Gene ontology (GO) annotations for mouse and human proteins.

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Figure 19

Protein evolution.

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Figure 20

Cytochrome P450 protein families in mouse, human and pufferfish.

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Figure 21

Protein evolution.

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Figure 22

Dot plot showing genomic alignment between mouse and human.

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Figure 23

Distribution of the conservation score S(R).

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Figure 24

Comparison of histograms for conservation scores for 100-bp windows in ancient transposons (red) with 100-bp windows in other kinds of regions (blue and green).

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Figure 25

Variation in conservation across a gene.

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Figure 26

The human spermidine synthase gene (SRM) on chromosome 1, involved in the biosynthesis of polyamines, and its mouse orthologue (Srm) on chromosome 4.

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Figure 27

Conservation scores for 50-bp windows in a 4.5-kb region containing the human insulin-like growth factor binding protein acid labile subunit (IGFALS) gene.

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Figure 28

Proportion of the human genome under selection and the probability of a genomic window to be under selection on the basis of conservation score.

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Figure 29

Estimated average number of substitutions per site in ancestral repeat sites (t_AR) (red) and in fourfold degenerate (4D) sites (t_4D) (blue) for each human chromosome.

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