FIGURE 18. Gene ontology (GO) annotations for mouse and human proteins.

From the following article:

Initial sequencing and comparative analysis of the mouse genome

and Mouse Genome Sequencing Consortium

Nature 420, 520-562(5 December 2002)

doi:10.1038/nature01262

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The GO terms assigned to mouse (blue) and human (red) proteins based on sequence matches to InterPro domains are grouped into approximately a dozen categories. These categories fell within each of the larger ontologies of cellular component (a) molecular function (b) and biological process (c) (D. Hill, personal communication). In general, mouse has a similar percentage of proteins compared with human in most categories. The apparently significant difference between the number of mouse and human proteins in the translational apparatus category of the cellular component ontology may be due to ribosomal protein pseudogenes incorrectly assigned as genes in mouse.

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