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Nature 420, 365-366 (28 November 2002) | doi:10.1038/420365a
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Faculty Position in Chromosome and Cell Cycle Research
- OMRF
- Oklahoma City, OK 73104, United States
Neuroscience Faculty Positions
- University of Tennessee Health Science Center
- Memphis, Tennessee, USA
Human genetics: Mystery of the mutagenic male
Laurence D. Hurst1 & Hans Ellegren2
Abstract
Old fathers are the source of more genetic mutations in their offspring than either young fathers or mothers of any age. But the apparently most plausible explanation for this effect might not hold.
Mutations are the raw material for evolution, and the cause of genetic disease. But how do they arise?
- Laurence D. Hurst is in the Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
e-mail: Email: l.d.hurst@bath.ac.uk - Hans Ellegren is in the Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, 752-36 Uppsala, Sweden.
e-mail: Email: hans.ellegren@ebc.uu.se
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