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TY  - JOUR
AU  - Saltiel, A. R.
AU  - Kahn, C. R.
TI  - Insulin signalling and the regulation of glucose and lipid metabolism
JO  - Nature
PY  - 2001///
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M3  - 10.1038/414799a
N1  - 10.1038/414799a
UR  - http://dx.doi.org/10.1038/414799a
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TY  - JOUR
AU  - Aguirre, V.
AU  - Uchida, T.
AU  - Yenush, L.
AU  - Davis, R.
AU  - White, M. F.
TI  - The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307
JO  - J. Biol. Chem.
PY  - 2000///
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TY  - JOUR
AU  - Sethi, J. K.
AU  - Hotamisligil, G. S.
TI  - The role of TNF alpha in adipocyte metabolism
JO  - Semin. Cell. Dev. Biol.
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AU  - Boden, G.
TI  - Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
JO  - Diabetes
PY  - 1997///
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TI  - The disease burden associated with overweight and obesity
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AU  - Wiesbrock, S. M.
AU  - Marino, M. W.
AU  - Hotamisligil, G. S.
TI  - Protection from obesity-induced insulin resistance in mice lacking TNF-[alpha] function
JO  - Nature
PY  - 1997///
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AU  - Hotamisligil, G. S.
AU  - Spiegelman, B. M.
TI  - Diabetes Mellitus
PY  - 2000///
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AU  - Chang, L.
AU  - Karin, M.
TI  - Mammalian MAP kinase signalling cascades
JO  - Nature
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TY  - JOUR
AU  - Shin, E. A.
TI  - Arachidonic acid induces the activation of the stress-activated protein kinase, membrane ruffling and H2O2 production via a small GTPase Rac1
JO  - FEBS Lett.
PY  - 1999///
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AU  - Rizzo, M. T.
AU  - Leaver, A. H.
AU  - Yu, W. M.
AU  - Kovacs, R. J.
TI  - Arachidonic acid induces mobilization of calcium stores and c-jun gene expression: evidence that intracellular calcium release is associated with c-jun activation
JO  - Prostaglandins Leukot. Essent. Fatty Acids
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TI  - Sounding the alarm: protein kinase cascades activated by stress and inflammation
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TY  - JOUR
AU  - Yamauchi, T.
TI  - The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
JO  - Nature Med.
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AU  - Berg, A. H.
AU  - Combs, T. P.
AU  - Du, X.
AU  - Brownlee, M.
AU  - Scherer, P. E.
TI  - The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
JO  - Nature Med.
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AU  - Steppan, C. M.
TI  - The hormone resistin links obesity to diabetes
JO  - Nature
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AU  - Kim, K. H.
AU  - Lee, K.
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TI  - A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation
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TY  - JOUR
AU  - Davis, R. J.
TI  - Signal transduction by the JNK group of MAP kinases
JO  - Cell
PY  - 2000///
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TY  - JOUR
AU  - Dong, C.
TI  - Defective T cell differentiation in the absence of Jnk1
JO  - Science
PY  - 1998///
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TY  - JOUR
AU  - Sabapathy, K.
TI  - JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
JO  - Curr. Biol.
PY  - 1999///
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TY  - JOUR
AU  - Sabapathy, K.
TI  - c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
JO  - J. Exp. Med.
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AU  - Shulman, G. I.
TI  - Cellular mechanisms of insulin resistance
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AU  - Hotamisligil, G. H.
TI  - IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-[alpha]- and obesity-induced insulin resistance
JO  - Science
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AU  - Griffin, M. E.
TI  - Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
JO  - Diabetes
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AU  - Waeber, G.
TI  - The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
JO  - Nature Genet.
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AU  - Hibi, M.
AU  - Lin, A.
AU  - Smeal, T.
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AU  - Karin, M.
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JO  - Genes Dev.
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AU  - Uysal, K. T.
AU  - Scheja, L.
AU  - Wiesbrock, S. M.
AU  - Bonner-Weir, S.
AU  - Hotamisligil, G. S.
TI  - Improved glucose and lipid metabolism in genetically obese mice lacking aP2
JO  - Endocrinology
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TY  - JOUR
AU  - Bennett, B. L.
TI  - SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
JO  - Proc. Natl Acad. Sci. USA
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