FIGURE 2. p75 is required for the inhibitory activities of myelin inhibitors.
From the following article:
p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
Kevin C. Wang, Jieun A. Kim, Rajeev Sivasankaran, Rosalind Segal and Zhigang He
Nature 420, 74-78(7 November 2002)
doi:10.1038/nature01176
a, b, Quantification of neurite length from adult DRG neurons (a) or P7 CGNs (b) from wild-type (control) and p75-/- (knockout, KO) mice on different immobilized substrates. The mean 
s.e.m. from a total of 1,211 (CGNs) or 923 (DRG) neurons from 3–4 experiments are presented. Statistical analysis was by one-way analysis of variance (ANOVA) (F = 37.55, degrees of freedom, d.f. = 1,210, P < 0.0001 for CGNs; F = 41.64, d.f. = 922, P < 0.0001 for DRGs), using a post-hoc Fisher protected test. All of the knockout groups on inhibitory substrates are significantly different from controls plated on the same substrates.
