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From the following article:

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1gamma by the FERM domain of talin

Gilbert Di Paolo, Lorenzo Pellegrini, Kresimir Letinic, Gianluca Cestra, Roberto Zoncu, Sergei Voronov, Sunghoe Chang, Jun Guo, Markus R. Wenk and Pietro De Camilli

Nature 420, 85-89(7 November 2002)

doi:10.1038/nature01147

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

The 90K splice variant of PtdInsPKIgamma is targeted to focal adhesion plaques in non-neuronal cells.

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Figure 2 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 2

Interaction of PtdInsPKIgamma-90, via a short amino acid sequence present in its 28aa-tail, with the FERM domain of talin.

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Figure 3 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 3

The interaction between talin and PtdInsPKIgamma-90 occurs physiologically in brain.

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Figure 4

Disruption of normal phosphoinositide metabolism at focal adhesion plaques interferes with cell adhesion in NIH 3T3 cells.

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