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From the following article:

N-CoR controls differentiation of neural stem cells into astrocytes

Ola Hermanson, Kristen Jepsen and Michael G. Rosenfeld

Nature 419, 934-939(31 October 2002)

doi:10.1038/nature01156

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

N-CoR is a regulator of neural stem cell state.

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Figure 2

The subcellular localization of N-CoR is altered by CNTF, and nuclear N-CoR represses CNTF-mediated astroglia differentiation and GFAP expression.

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Figure 3

Akt1 kinase activation in neural stem cells is required for CNTF-mediated astroglia differentiation, GFAP expression, and re-localization of N-CoR.

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Figure 4

The subcellular localization of N-CoR is regulated through direct targeting by Akt1 kinase and protein phosphatase-1 (PP-1).

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