Brief Communications

Nature 419, 895-896 (31 October 2002) | doi:10.1038/419895a

Herbicides: Feminization of male frogs in the wild

Tyrone Hayes, Kelly Haston, Mable Tsui, Anhthu Hoang, Cathryn Haeffele & Aaron Vonk

Atrazine is the most commonly used herbicide in the United States and probably in the world1. Here we investigate the effects of exposure to water-borne atrazine contamination on wild leopard frogs (Rana pipiens) in different regions of the United States and find that 10–92% of males show gonadal abnormalities such as retarded development and hermaphroditism. These results are supported by laboratory observations, which together highlight concerns over the biological effects of environmental atrazine on amphibians.

  1. Laboratory for Integrative Studies in Amphibian Biology, Museum of Vertebrate Zoology, and Department of Integrative Biology, University of California, Berkeley, California 94720-3140, USA

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