Table of contents
Volume 419 Number 6909 pp3-862
Opinion
Looking after number one p763
A merger of University College London and Imperial College, the top two research universities in Britain's capital city, may not in itself create a combined institution that is more internationally competitive.
doi:10.1038/419763a
News
Universities face cash shortfall as stock-market slide hits charities p765
Declan Butler
doi:10.1038/419765a
Fatal rocket accident puts question mark over Soyuz's safety p766
David Adam
doi:10.1038/419766a
Spain's staff shortages leave astronomy plans up in the air p766
Monica Salomone
doi:10.1038/419766b
Super-enzyme patents get their day in court p767
David Cyranoski
doi:10.1038/419767a
Malta provides loophole for breast-cancer screen p767
Erika Check
doi:10.1038/419767b
Bioprospectors turn their gaze to Canada p768
Rex Dalton
doi:10.1038/419768a
Marie Curie doesn't live here, Japanese women say p768
David Cyranoski
doi:10.1038/419768b
Medical funding group calls for clamp-down on hype p769
David Adam
doi:10.1038/419769a
National academies slam Bush proposal for data security p769
Erika Check
doi:10.1038/419769b
news feature
Journals under pressure: Publish, and be damned... p772
Recent controversies over scientific fraud and other disputed findings have raised questions over the way in which journals select papers for publication. Is there a problem? And what more could be done to weed out dubious results? David Adam and Jonathan Knight investigate.
David Adam and Jonathan Knight
doi:10.1038/419772a
Correspondence
International unions concerned about biodata p777
Action must be taken now to ensure that data are safely archived and always accessible.
Jean Garnier and Herman J. C. Berendsen
doi:10.1038/419777a
Feeding the world p777
Catherine Badgley
doi:10.1038/419777b
Autumn Books
The gospel of inevitability p779
Was the Universe destined to lead to the evolution of humans?
Eörs Szathmáry reviews Life Evolving: Molecules, Mind, and Meaning by Christian de Duve
doi:10.1038/419779a
Universal values p780
Thanu Padmanabhan reviews The Constants of Nature by John Barrow
doi:10.1038/419780a
The last word on Darwin? p781
Ernst Mayr reviews Charles Darwin: The Power of Place by Janet Browne
doi:10.1038/419781a
Reaching for the Moon p782
Robert Bud reviews The Lunar Men: Five Friends Whose Curiosity Changed the World by Jenny Uglow
doi:10.1038/419782a
Einstein brought up to speed p783
Francis Everitt reviews The Curvature of Spacetime: Newton, Einstein, and Gravitation by Harald Fritzsch
doi:10.1038/419783a
A race through the dark p784
Sean Carroll reviews The Extravagant Universe: Exploding Stars, Dark Energy and the Accelerating Cosmos by Robert P. Kirshner
doi:10.1038/419784a
The breath of life and death p785
Thomas B. L. Kirkwood reviews Oxygen: The Molecule that Made the World by Nick Lane
doi:10.1038/419785a
Bringing scientists to life p786
Oliver Sacks reviews Eurekas and Euphorias: The Oxford Book of Scientific Anecdotes by Walter Gratzer
doi:10.1038/419786a
News and Views
Attophysics: Atomic photography p789
No ordinary camera can capture the motion of electrons inside an atom. But the advent of ultrafast laser pulses brings the necessary 'shutter speed' for snapping them as they tumble between energy levels close to the nucleus.
Louis F. DiMauro
doi:10.1038/419789a
Cell biology: Survival in three dimensions p790
Whether a cell lives or dies depends on various local cues. New work reveals that those cues include a cell's spatial relationship with its neighbours and polarized interactions with the adjacent extracellular matrix.
Kenneth M. Yamada and Katherine Clark
doi:10.1038/419790a
Planetary science: Earth's lunar attic p791
Rocks blasted long ago from the surface of Earth and other planets may be preserved on the Moon. Although hard to identify, they could hold a unique record of the chemical history of the planets and even evidence of life.
Clark R. Chapman
doi:10.1038/419791a
100 and 50 years ago p793
doi:10.1038/419793a
Ageing: The old worm turns more slowly p794
Detailed studies of cellular changes in ageing nematode worms show that they, like humans, suffer progressive muscle deterioration. Randomness of cell damage is another shared hallmark of the ageing process.
Thomas B. L. Kirkwood and Caleb E. Finch
doi:10.1038/419794a
Cancer: Pinning a change on p53 p795
An enzyme-induced conformational change is now implicated in activating the p53 protein, one of a cell's prime movers in preventing tumour development.
Kevin M. Ryan and Karen H. Vousden
doi:10.1038/419795a
Quantum physics: NOT logic p797
A direct quantum equivalent of an electronic NOT gate is impossible. But the best possible approximation to the universal NOT transformation has now been demonstrated using photons.
Nicolas Gisin
doi:10.1038/419797a
Circadian rhythms: Finer clock control p798
The clock that governs circadian rhythms is based on a molecular feedback loop, which has just become more complex — two more proteins have been identified as likely components of the loop.
J. D. Alvarez and Amita Sehgal
doi:10.1038/419798a
Atmospheric science: Plumes and flumes p798
Modelling work with a water flume shows how the alignment of smokestacks with respect to the prevailing wind may affect the behaviour of smoke plumes.
Jim Gillon
doi:10.1038/419798b
correction p799
doi:10.1038/419799a
Obituary: David Keynes Hill (1915–2002) p800
A. F. Huxley
doi:10.1038/419800a
Brief Communications
Nanotechnology: Spinning continuous carbon nanotube yarns p801
Carbon nanotubes weave their way into a range of imaginative macroscopic applications.
Kaili Jiang, Qunqing Li and Shoushan Fan
doi:10.1038/419801a
First paragraph | Full Text | PDF (103K)
Olfactory plasticity: One nostril knows what the other learns p802
Joel D. Mainland, Elizabeth A. Bremner, Natasha Young, Brad N. Johnson, Rehan M. Khan, Moustafa Bensafi and Noam Sobel
doi:10.1038/419802a
First paragraph | Full Text | PDF (41K)
Light microscopy (communication arising): Beyond the diffraction limit p802
Pekka Hänninen
doi:10.1038/419802b
First paragraph | Full Text | PDF (41K)
Articles
Time-resolved atomic inner-shell spectroscopy p803
M. Drescher, M. Hentschel, R. Kienberger, M. Uiberacker, V. Yakovlev, A. Scrinzi, Th. Westerwalbesloh, U. Kleineberg, U. Heinzmann and F. Krausz
doi:10.1038/nature01143
Abstract | Full Text | PDF (314K) | Supplementary information
See also: News and Views by DiMauro
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans p808
Laura A. Herndon, Peter J. Schmeissner, Justyna M. Dudaronek, Paula A. Brown, Kristin M. Listner, Yuko Sakano, Marie C. Paupard, David H. Hall and Monica Driscoll
doi:10.1038/nature01135
Abstract | Full Text | PDF (479K) | Supplementary information
See also: News and Views by Kirkwood & Finch
Letters to Nature
Experimental realization of the quantum universal NOT gate p815
F. De Martini,
V. Bu
ek,
F. Sciarrino
and
C. Sias
doi:10.1038/nature01093
First paragraph | Full Text | PDF (306K)
See also: News and Views by Gisin
Observation of coupled magnetic and electric domains p818
M. Fiebig, Th. Lottermoser, D. Fröhlich, A. V. Goltsev and R. V. Pisarev
doi:10.1038/nature01077
First paragraph | Full Text | PDF (278K)
Millennial-scale storminess variability in the northeastern United States during the Holocene epoch p821
Anders J. Noren, Paul R. Bierman, Eric J. Steig, Andrea Lini and John Southon
doi:10.1038/nature01132
First paragraph | Full Text | PDF (273K) | Supplementary information
The strength of Mg0.9Fe0.1SiO3 perovskite at high pressure and temperature p824
Jiuhua Chen, Donald J. Weidner and Michael T. Vaughan
doi:10.1038/nature01130
First paragraph | Full Text | PDF (197K)
Contemporary fisherian life-history evolution in small salmonid populations p826
Mikko T. Koskinen, Thrond O. Haugen and Craig R. Primmer
doi:10.1038/nature01029
First paragraph | Full Text | PDF (377K) | Supplementary information
Paternal inheritance of a female moth's mating preference p830
Vikram K. Iyengar, H. Kern Reeve and Thomas Eisner
doi:10.1038/nature01027
First paragraph | Full Text | PDF (142K)
Detecting recent positive selection in the human genome from haplotype structure p832
Pardis C. Sabeti, David E. Reich, John M. Higgins, Haninah Z. P. Levine, Daniel J. Richter, Stephen F. Schaffner, Stacey B. Gabriel, Jill V. Platko, Nick J. Patterson, Gavin J. McDonald, Hans C. Ackerman, Sarah J. Campbell, David Altshuler, Richard Cooper, Dominic Kwiatkowski, Ryk Ward and Eric S. Lander
doi:10.1038/nature01140
First paragraph | Full Text | PDF (607K) | Supplementary information
Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages p837
Roope Männikkö, Fredrik Elinder and H. Peter Larsson
doi:10.1038/nature01038
First paragraph | Full Text | PDF (541K) | Supplementary information
Dec1 and Dec2 are regulators of the mammalian molecular clock p841
Sato Honma, Takeshi Kawamoto, Yumiko Takagi, Katsumi Fujimoto, Fuyuki Sato, Mitsuhide Noshiro, Yukio Kato and Ken-ichi Honma
doi:10.1038/nature01123
First paragraph | Full Text | PDF (296K)
See also: News and Views by Alvarez & Sehgal
Direct observation of ligand recognition by T cells p845
Darrell J. Irvine, Marco A. Purbhoo, Michelle Krogsgaard and Mark M. Davis
doi:10.1038/nature01076
First paragraph | Full Text | PDF (541K) | Supplementary information
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response p849
Hongwu Zheng, Han You, Xiao Zhen Zhou, Stephen A. Murray, Takafumi Uchida, Gerburg Wulf, Ling Gu, Xiaoren Tang, Kun Ping Lu and Zhi-Xiong Jim Xiao
doi:10.1038/nature01116
First paragraph | Full Text | PDF (513K) | Supplementary information
See also: News and Views by Ryan & Vousden
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults p853
Paola Zacchi, Monica Gostissa, Takafumi Uchida, Clio Salvagno, Fabio Avolio, Stefano Volinia, Ze'ev Ronai, Giovanni Blandino, Claudio Schneider and Giannino Del Sal
doi:10.1038/nature01120
First paragraph | Full Text | PDF (476K) | Supplementary information
See also: News and Views by Ryan & Vousden
Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1 p857
Christian Beisel, Axel Imhof, Jaime Greene, Elisabeth Kremmer and Frank Sauer
doi:10.1038/nature01126
First paragraph | Full Text | PDF (401K) | Supplementary information
erratum: Self-organization of supramolecular helical dendrimers into complex electronic materials p862
V. Percec, M. Glodde, T. K. Bera, Y. Miura, I. Shiyanovskaya, K. D. Singer, V. S. K. Balagurusamy, P. A. Heiney, I. Schnell, A. Rapp, H.-W. Spiess, S. D. Hudson and H. Duan
doi:10.1038/nature01161
