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Cancer

The silence of the genes

The discovery that a transcriptional repressor is turned on in prostate tumours as they become metastatic, leading to the silencing of many genes, suggests a new mechanism for tumour progression.

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Figure 1: Tumour progression and transcriptional repressor proteins.

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Correspondence to Bruce R. Zetter or Jacqueline Banyard.

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Zetter, B., Banyard, J. The silence of the genes. Nature 419, 572–573 (2002). https://doi.org/10.1038/419572a

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