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Nature 419, 546 (10 October 2002) | doi:10.1038/419546b

Call for clinical-trial reform leaves critics unmoved

Kendall Powell

Medical watchdog groups in the United States say they are becoming frustrated that reforms of the clinical-research system have failed to materialize, despite repeated calls for tougher regulation.On 3 October, the Institute of Medicine released a report calling for modest reforms of the system.