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Immunology

Survival of the fitters

A Correction to this article was published on 05 December 2002

Our immune system's ability to fight viruses inside our cells relies on viral protein fragments being displayed on the cell surface. The enzyme needed for the last step in this presentation process has now been discovered.

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Figure 1: Informing the immune system.

References

  1. Serwold, T. et al. Nature 419, 480–483 (2002).

    Article  ADS  CAS  Google Scholar 

  2. Falk, K., Rotzschke, O. & Rammensee, H.-G Nature 348, 248–251 (1990).

    Article  ADS  CAS  Google Scholar 

  3. Beninga, J., Rock, K. L. & Goldberg, A. L. J. Biol. Chem. 273, 18734–18742 (1998).

    Article  CAS  Google Scholar 

  4. Stoltze, L. et al. Nature Immunol. 1, 413–418 (2000).

    Article  CAS  Google Scholar 

  5. Brouwenstijn, N., Serwold, T. & Shastri, N. Immunity 15, 95–104 (2001).

    Article  CAS  Google Scholar 

  6. Fruci, D., Niedermann, G., Butler, R. H. & van Endert, P. M. Immunity 15, 467–476 (2001).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Hans-Georg Rammensee.

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Rammensee, HG. Survival of the fitters. Nature 419, 443–445 (2002). https://doi.org/10.1038/419443a

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