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Gene regulation

Reviving the message

Studies of developmental regulators in worms and cell-cycle regulators in yeast have revealed a new family of enzymes, which may affect the fate of specific messenger RNA molecules.

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Figure 1: A new type of RNA-modifying enzyme?
Figure 2: Structure of the mammalian nuclear poly(A) polymerase, with regions of similarity to GLD-2 and its relatives highlighted (colour code as in Fig. 1).

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Correspondence to Walter Keller.

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Keller, W., Martin, G. Reviving the message. Nature 419, 267–268 (2002). https://doi.org/10.1038/419267a

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