Table of contents


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Naturejobs

Prospects

Taking the initiative p3

Paul Smaglik

doi:10.1038/nj6904-03a


regions

Calling for entrepreneurs London p4

Paul Smaglik

doi:10.1038/nj6904-04a


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Opinion

More drugs, less protection p233

A study of the impact of the system of intellectual property rights on drug development has highlighted problems that must be addressed. An influential committee meeting this week has the power to bring about change, and should do so.

doi:10.1038/419233a


Improving proto-scientists' summers p233

Parents need to keep offspring occupied in the summer. Universities can help them — and brighten the future of science, too.

doi:10.1038/419233b


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News

Next-generation space telescope sets course for 2010 launch p235

Tony Reichhardt

doi:10.1038/419235a


US return may boost 'S' in UNESCO p235

Jonathan Knight

doi:10.1038/419235b


Prion research stepped up as fear grows of deer disease p236

Rex Dalton and Erika Check

doi:10.1038/419236a


Japan celebrates safe launch after string of problems p236

David Cyranoski

doi:10.1038/419236b


Kosovo's ethnic divide blights UN science rebuilding plans p237

Quirin Schiermeier

doi:10.1038/419237a


Second round of gene sequencing goes down to the farm p237

Kendall Powell

doi:10.1038/419237b


India shuts door on embryonic export market p238

K. S. Jayaraman

doi:10.1038/419238a


Telescope to track speedy satellites p238

Geoff Brumfiel

doi:10.1038/419238b


Pyramid find reopens lost chapter of history p239

Alison Abbott

doi:10.1038/419239a


'Unusual forces' are pushing journal market off course p239

Sally Goodman

doi:10.1038/419239b


news in brief p240

doi:10.1038/419240a


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news feature

Behavioural ecology: Nosy neighbours p242

By snooping on one another's social lives, animals can work out how to behave when they meet in the future. John Whitfield listens in on the natural world's eavesdroppers.

John Whitfield

doi:10.1038/419242a


Physics meets biology: Bridging the culture gap p244

Molecular biologists are deluged with data, and physicists, used to reducing complex systems to basic principles, might help to make sense of it all. But bringing the two disciplines together isn't easy, says Jonathan Knight.

Jonathan Knight

doi:10.1038/419244a


Top

Correspondence

The many dangers of relying on a DNA database p247

It may be convenient for the police, but the use of DNA as evidence is full of pitfalls.

Ralph Kirby

doi:10.1038/419247a


Could we trust every future government? p247

Adrian Bowyer

doi:10.1038/419247b


Planted 'evidence' weakens case for DNA p247

Oliver Flint

doi:10.1038/419247c


Free consanguinity testing for all p247

Panos Ioannou

doi:10.1038/419247d


Why response-mode research loses out p248

Bernard L. Cohen

doi:10.1038/419248a


Europe is not yet ready for a research council p248

Barry Holland

doi:10.1038/419248b


Element of confusion p248

Richard Joyner

doi:10.1038/419248c


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Commentary

A fresh start for European science p249

The scientific community must take up the challenges set by EU objectives.

doi:10.1038/419249a


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Book Reviews

Nurturing a view of human nature p251

Our genes ensure that our minds are never 'blank slates'.

David L. Hull reviews The Blank Slate: The Modern Denial of Human Nature by Steven Pinker

doi:10.1038/419251a


Reptiles of the republic p252

doi:10.1038/419252a


Dog-days at the data factory p252

Steve Sturdy reviews Pavlov's Physiology Factory: Experiment, Interpretation, Laboratory Enterprise by Daniel P. Todes

doi:10.1038/419252b


A stroll with the moulds p253

Elio Schaechter reviews Mr. Bloomfield's Orchard: The Mysterious World of Mushrooms, Molds, and Mycologists by Nicholas P. Money

doi:10.1038/419253a


Top

concepts

Awareness: Animal reflections p255

Marc Bekoff

doi:10.1038/419255a


Top

News and Views

Earth Science: Parkfield's unfulfilled promise p257

The idea that earthquakes are 'time-predictable' underlies many of today's probabilistic forecasts. In a key test on California's San Andreas fault the concept is found wanting, but the news may not be all bad.

Ross S. Stein

doi:10.1038/419257a


Neurobiology: Plasticity and the older owl p258

Age reduces the brain's ability to adapt to change. But a surprising measure of neural adaptation does occur, at least in one experimental situation, if change is introduced bit by bit.

Hemai Parthasarathy

doi:10.1038/419258a


Gamma-ray bursts: Light from darkness p259

Telescopes must respond quickly to pinpoint transient gamma-ray bursts and pick up their afterglow. Mysterious 'dark' bursts seemed to produce no light at optical wavelengths, but a faint signal has now been detected.

Gerald J. Fishman

doi:10.1038/419259a


Developmental biology: Sharp peaks from shallow sources p261

The use of mathematical modelling to formulate and test theories is still quite rare in biology. It has now been applied to show how a robust, sharp peak of signalling molecules can be formed in developing fruitfly embryos.

Hans Meinhardt and Siegfried Roth

doi:10.1038/419261a


Cell biology: Proteins tracked in a flash p262

Deepa Nath

doi:10.1038/419262a


Physiology: Unhealthy surprises p263

Fluctuations in heart rate can signal disease and may prove fatal. A measurement, based on entropy, of how 'surprising' the beat irregularity is, distinguishes healthy hearts from those suffering common forms of illness.

Dante R. Chialvo

doi:10.1038/419263a


Conservation biology: Science, sex and the kakapo p265

Sex-allocation theory predicts how the sex ratio of offspring should vary with the mother's physical condition. Applying this theory has helped in retrieving a charismatic parrot from the edge of extinction.

William J. Sutherland

doi:10.1038/419265a


100 and 50 years ago p265

doi:10.1038/419265b


Chemical physics: A delayed reaction p266

The simple hydrogen exchange reaction was well understood until an unexpected effect emerged in detailed experimental measurements of the process. An explanation for this effect has now been found.

David E. Manolopoulos

doi:10.1038/419266a


Gene regulation: Reviving the message p267

Studies of developmental regulators in worms and cell-cycle regulators in yeast have revealed a new family of enzymes, which may affect the fate of specific messenger RNA molecules.

Walter Keller and Georges Martin

doi:10.1038/419267a


Top

Brief Communications

Neuropsychology: Stimulating illusory own-body perceptions p269

The part of the brain that can induce out-of-body experiences has been located.

Olaf Blanke, Stphanie Ortigue, Theodor Landis and Margitta Seeck

doi:10.1038/419269a


Eukaryotic evolution: Early origin of canonical introns p270

Alastair G. B. Simpson, Erin K. MacQuarrie and Andrew J. Roger

doi:10.1038/419270a


Top

Article

Structure of the Sec23/24–Sar1 pre-budding complex of the COPII vesicle coat p271

Xiping Bi, Richard A. Corpina and Jonathan Goldberg

doi:10.1038/nature01040


Top

Letters to Nature

Allowed and forbidden transitions in artificial hydrogen and helium atoms p278

Toshimasa Fujisawa, David Guy Austing, Yasuhiro Tokura, Yoshiro Hirayama and Seigo Tarucha

doi:10.1038/nature00976


Forward scattering due to slow-down of the intermediate in the H + HD right arrow D + H2 reaction p281

Steven A. Harich, Dongxu Dai, Chia C. Wang, Xueming Yang, Sheng Der Chao and Rex T. Skodje

doi:10.1038/nature01068

See also: News and Views by Manolopoulos


An all-organic composite actuator material with a high dielectric constant p284

Q. M. Zhang, Hengfeng Li, Martin Poh, Feng Xia, Z.-Y. Cheng, Haisheng Xu and Cheng Huang

doi:10.1038/nature01021


Testing time-predictable earthquake recurrence by direct measurement of strain accumulation and release p287

Jessica Murray and Paul Segall

doi:10.1038/nature00984

See also: News and Views by Stein


An unusual oviraptorosaurian dinosaur from China p291

Xing Xu, Yen-Nien Cheng, Xiao-Lin Wang and Chun-Hsiang Chang

doi:10.1038/nature00966


Incremental training increases the plasticity of the auditory space map in adult barn owls p293

Brie A. Linkenhoker and Eric I. Knudsen

doi:10.1038/nature01002

See also: News and Views by Parthasarathy


Odorant receptors instruct functional circuitry in the mouse olfactory bulb p296

Leonardo Belluscio, Claudia Lodovichi, Paul Feinstein, Peter Mombaerts and Lawrence C. Katz

doi:10.1038/nature01001


Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier p300

M. Charles Liberman, Jiangang Gao, David Z. Z. He, Xudong Wu, Shuping Jia and Jian Zuo

doi:10.1038/nature01059


Robustness of the BMP morphogen gradient in Drosophila embryonic patterning p304

Avigdor Eldar, Ruslan Dorfman, Daniel Weiss, Hilary Ashe, Ben-Zion Shilo and Naama Barkai

doi:10.1038/nature01061

See also: News and Views by Meinhardt & Roth


Molecular basis of seasonal time measurement in Arabidopsis p308

Marcelo J. Yanovsky and Steve A. Kay

doi:10.1038/nature00996


A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans p312

Liaoteng Wang, Christian R. Eckmann, Lisa C. Kadyk, Marvin Wickens and Judith Kimble

doi:10.1038/nature01039

See also: News and Views by Keller & Martin


Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress p316

Geert J. P. L. Kops, Tobias B. Dansen, Paulien E. Polderman, Ingrid Saarloos, Karel W. A. Wirtz, Paul J. Coffer, Ting-T. Huang, Johannes L. Bos, René H. Medema and Boudewijn M. T. Burgering

doi:10.1038/nature01036


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