Table of contents
Volume 419 Number 6904 pp3-321
Naturejobs
ProspectsTaking the initiative p3
Paul Smaglik
doi:10.1038/nj6904-03a
regions
Calling for entrepreneurs London p4
Paul Smaglik
doi:10.1038/nj6904-04a
Opinion
More drugs, less protection p233
A study of the impact of the system of intellectual property rights on drug development has highlighted problems that must be addressed. An influential committee meeting this week has the power to bring about change, and should do so.
doi:10.1038/419233a
Improving proto-scientists' summers p233
Parents need to keep offspring occupied in the summer. Universities can help them — and brighten the future of science, too.
doi:10.1038/419233b
News
Next-generation space telescope sets course for 2010 launch p235
Tony Reichhardt
doi:10.1038/419235a
US return may boost 'S' in UNESCO p235
Jonathan Knight
doi:10.1038/419235b
Prion research stepped up as fear grows of deer disease p236
Rex Dalton and Erika Check
doi:10.1038/419236a
Japan celebrates safe launch after string of problems p236
David Cyranoski
doi:10.1038/419236b
Kosovo's ethnic divide blights UN science rebuilding plans p237
Quirin Schiermeier
doi:10.1038/419237a
Second round of gene sequencing goes down to the farm p237
Kendall Powell
doi:10.1038/419237b
India shuts door on embryonic export market p238
K. S. Jayaraman
doi:10.1038/419238a
Telescope to track speedy satellites p238
Geoff Brumfiel
doi:10.1038/419238b
Pyramid find reopens lost chapter of history p239
Alison Abbott
doi:10.1038/419239a
'Unusual forces' are pushing journal market off course p239
Sally Goodman
doi:10.1038/419239b
news feature
Behavioural ecology: Nosy neighbours p242
By snooping on one another's social lives, animals can work out how to behave when they meet in the future. John Whitfield listens in on the natural world's eavesdroppers.
John Whitfield
doi:10.1038/419242a
Physics meets biology: Bridging the culture gap p244
Molecular biologists are deluged with data, and physicists, used to reducing complex systems to basic principles, might help to make sense of it all. But bringing the two disciplines together isn't easy, says Jonathan Knight.
Jonathan Knight
doi:10.1038/419244a
Correspondence
The many dangers of relying on a DNA database p247
It may be convenient for the police, but the use of DNA as evidence is full of pitfalls.
Ralph Kirby
doi:10.1038/419247a
Could we trust every future government? p247
Adrian Bowyer
doi:10.1038/419247b
Planted 'evidence' weakens case for DNA p247
Oliver Flint
doi:10.1038/419247c
Free consanguinity testing for all p247
Panos Ioannou
doi:10.1038/419247d
Why response-mode research loses out p248
Bernard L. Cohen
doi:10.1038/419248a
Europe is not yet ready for a research council p248
Barry Holland
doi:10.1038/419248b
Element of confusion p248
Richard Joyner
doi:10.1038/419248c
Commentary
A fresh start for European science p249
The scientific community must take up the challenges set by EU objectives.
doi:10.1038/419249a
Book Reviews
Nurturing a view of human nature p251
Our genes ensure that our minds are never 'blank slates'.
David L. Hull reviews The Blank Slate: The Modern Denial of Human Nature by Steven Pinker
doi:10.1038/419251a
Reptiles of the republic p252
doi:10.1038/419252a
Dog-days at the data factory p252
Steve Sturdy reviews Pavlov's Physiology Factory: Experiment, Interpretation, Laboratory Enterprise by Daniel P. Todes
doi:10.1038/419252b
A stroll with the moulds p253
Elio Schaechter reviews Mr. Bloomfield's Orchard: The Mysterious World of Mushrooms, Molds, and Mycologists by Nicholas P. Money
doi:10.1038/419253a
News and Views
Earth Science: Parkfield's unfulfilled promise p257
The idea that earthquakes are 'time-predictable' underlies many of today's probabilistic forecasts. In a key test on California's San Andreas fault the concept is found wanting, but the news may not be all bad.
Ross S. Stein
doi:10.1038/419257a
Neurobiology: Plasticity and the older owl p258
Age reduces the brain's ability to adapt to change. But a surprising measure of neural adaptation does occur, at least in one experimental situation, if change is introduced bit by bit.
Hemai Parthasarathy
doi:10.1038/419258a
Gamma-ray bursts: Light from darkness p259
Telescopes must respond quickly to pinpoint transient gamma-ray bursts and pick up their afterglow. Mysterious 'dark' bursts seemed to produce no light at optical wavelengths, but a faint signal has now been detected.
Gerald J. Fishman
doi:10.1038/419259a
Developmental biology: Sharp peaks from shallow sources p261
The use of mathematical modelling to formulate and test theories is still quite rare in biology. It has now been applied to show how a robust, sharp peak of signalling molecules can be formed in developing fruitfly embryos.
Hans Meinhardt and Siegfried Roth
doi:10.1038/419261a
Cell biology: Proteins tracked in a flash p262
Deepa Nath
doi:10.1038/419262a
Physiology: Unhealthy surprises p263
Fluctuations in heart rate can signal disease and may prove fatal. A measurement, based on entropy, of how 'surprising' the beat irregularity is, distinguishes healthy hearts from those suffering common forms of illness.
Dante R. Chialvo
doi:10.1038/419263a
Conservation biology: Science, sex and the kakapo p265
Sex-allocation theory predicts how the sex ratio of offspring should vary with the mother's physical condition. Applying this theory has helped in retrieving a charismatic parrot from the edge of extinction.
William J. Sutherland
doi:10.1038/419265a
100 and 50 years ago p265
doi:10.1038/419265b
Chemical physics: A delayed reaction p266
The simple hydrogen exchange reaction was well understood until an unexpected effect emerged in detailed experimental measurements of the process. An explanation for this effect has now been found.
David E. Manolopoulos
doi:10.1038/419266a
Gene regulation: Reviving the message p267
Studies of developmental regulators in worms and cell-cycle regulators in yeast have revealed a new family of enzymes, which may affect the fate of specific messenger RNA molecules.
Walter Keller and Georges Martin
doi:10.1038/419267a
Brief Communications
Neuropsychology: Stimulating illusory own-body perceptions p269
The part of the brain that can induce out-of-body experiences has been located.
Olaf Blanke, Stphanie Ortigue, Theodor Landis and Margitta Seeck
doi:10.1038/419269a
First paragraph | Full Text | PDF (97K)
Eukaryotic evolution: Early origin of canonical introns p270
Alastair G. B. Simpson, Erin K. MacQuarrie and Andrew J. Roger
doi:10.1038/419270a
First paragraph | Full Text | PDF (47K)
Article
Structure of the Sec23/24–Sar1 pre-budding complex of the COPII vesicle coat p271
Xiping Bi, Richard A. Corpina and Jonathan Goldberg
doi:10.1038/nature01040
Abstract | Full Text | PDF (712K) | Supplementary information
Letters to Nature
Allowed and forbidden transitions in artificial hydrogen and helium atoms p278
Toshimasa Fujisawa, David Guy Austing, Yasuhiro Tokura, Yoshiro Hirayama and Seigo Tarucha
doi:10.1038/nature00976
First paragraph | Full Text | PDF (336K)
Forward scattering due to slow-down of the intermediate in the H + HD 
D + H2 reaction p281
Steven A. Harich, Dongxu Dai, Chia C. Wang, Xueming Yang, Sheng Der Chao and Rex T. Skodje
doi:10.1038/nature01068
First paragraph | Full Text | PDF (247K)
See also: News and Views by Manolopoulos
An all-organic composite actuator material with a high dielectric constant p284
Q. M. Zhang, Hengfeng Li, Martin Poh, Feng Xia, Z.-Y. Cheng, Haisheng Xu and Cheng Huang
doi:10.1038/nature01021
First paragraph | Full Text | PDF (177K)
Testing time-predictable earthquake recurrence by direct measurement of strain accumulation and release p287
Jessica Murray and Paul Segall
doi:10.1038/nature00984
First paragraph | Full Text | PDF (293K)
See also: News and Views by Stein
An unusual oviraptorosaurian dinosaur from China p291
Xing Xu, Yen-Nien Cheng, Xiao-Lin Wang and Chun-Hsiang Chang
doi:10.1038/nature00966
First paragraph | Full Text | PDF (227K) | Supplementary information
Incremental training increases the plasticity of the auditory space map in adult barn owls p293
Brie A. Linkenhoker and Eric I. Knudsen
doi:10.1038/nature01002
First paragraph | Full Text | PDF (277K)
See also: News and Views by Parthasarathy
Odorant receptors instruct functional circuitry in the mouse olfactory bulb p296
Leonardo Belluscio, Claudia Lodovichi, Paul Feinstein, Peter Mombaerts and Lawrence C. Katz
doi:10.1038/nature01001
First paragraph | Full Text | PDF (374K)
Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier p300
M. Charles Liberman, Jiangang Gao, David Z. Z. He, Xudong Wu, Shuping Jia and Jian Zuo
doi:10.1038/nature01059
First paragraph | Full Text | PDF (408K)
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning p304
Avigdor Eldar, Ruslan Dorfman, Daniel Weiss, Hilary Ashe, Ben-Zion Shilo and Naama Barkai
doi:10.1038/nature01061
First paragraph | Full Text | PDF (532K) | Supplementary information
See also: News and Views by Meinhardt & Roth
Molecular basis of seasonal time measurement in Arabidopsis p308
Marcelo J. Yanovsky and Steve A. Kay
doi:10.1038/nature00996
First paragraph | Full Text | PDF (302K) | Supplementary information
A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans p312
Liaoteng Wang, Christian R. Eckmann, Lisa C. Kadyk, Marvin Wickens and Judith Kimble
doi:10.1038/nature01039
First paragraph | Full Text | PDF (653K)
See also: News and Views by Keller & Martin
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress p316
Geert J. P. L. Kops, Tobias B. Dansen, Paulien E. Polderman, Ingrid Saarloos, Karel W. A. Wirtz, Paul J. Coffer, Ting-T. Huang, Johannes L. Bos, René H. Medema and Boudewijn M. T. Burgering
doi:10.1038/nature01036
First paragraph | Full Text | PDF (378K) | Supplementary information
