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Nature 419, 127-128 (12 September 2002) | doi:10.1038/419127a

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Cancer: Stuck at first base

Louise van der Weyden, Jos Jonkers & Allan Bradley

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People with the genetic disease Peutz–Jeghers syndrome have many intestinal polyps — benign tissue outgrowths. These seldom become malignant, and the reason may lie in the properties of the affected gene.

Several inherited human diseases are characterized by the formation of polyps in the gut. Polyps are benign outgrowths of tissue with a disordered structure.

  1. Louise van der Weyden, Jos Jonkers and Allan Bradley are at the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.
    email:Email: abradley@sanger.ac.uk