Provider: Nature Publishing Group Content: application/x-research-info-systems TY - JOUR AU - Sukharev, S. I. AU - Blount, P. AU - Martinac, B. AU - Kung, C. TI - Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities JO - Annu. Rev. Physiol. PY - 1997/// VL - 59 SP - 633 EP - 657 M3 - 10.1146/annurev.physiol.59.1.633 N1 - 10.1146/annurev.physiol.59.1.633 UR - http://dx.doi.org/10.1146/annurev.physiol.59.1.633 ER - TY - JOUR AU - Wood, J. M. TI - Osmosensing by bacteria: signals and membrane-based sensors JO - Microbiol. Mol. Biol. Rev. PY - 1999/// VL - 63 SP - 230 EP - 262 ER - TY - JOUR AU - Hamill, O. P. AU - Martinac, B. TI - Molecular basis of mechanotransduction in living cells JO - Physiol. Rev. PY - 2001/// VL - 81 SP - 685 EP - 740 ER - TY - JOUR AU - Martinac, B. AU - Adler, J. AU - Kung, C. TI - Mechanosensitive ion channels of E. coli activated by amphipaths JO - Nature PY - 1990/// VL - 348 SP - 261 EP - 263 M3 - 10.1038/348261a0 N1 - 10.1038/348261a0 UR - http://dx.doi.org/10.1038/348261a0 ER - TY - JOUR AU - Sukharev, S. I. AU - Blount, P. AU - Martinac, B. AU - Blattner, F. R. AU - Kung, C. TI - A large-conductance mechanosensitive channel in E. coli encoded by mscL alone JO - Nature PY - 1994/// VL - 368 SP - 265 EP - 268 M3 - 10.1038/368265a0 N1 - 10.1038/368265a0 UR - http://dx.doi.org/10.1038/368265a0 ER - TY - JOUR AU - Patel, A. J. TI - A mammalian two pore domain mechano-gated S-like K + channel JO - EMBO J. PY - 1998/// VL - 17 SP - 4283 EP - 4290 M3 - 10.1093/emboj/17.15.4283 N1 - 10.1093/emboj/17.15.4283 UR - http://dx.doi.org/10.1093/emboj/17.15.4283 ER - TY - JOUR AU - Levina, N. TI - Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS ativity JO - EMBO J. PY - 1999/// VL - 18 SP - 1730 EP - 1737 M3 - 10.1093/emboj/18.7.1730 N1 - 10.1093/emboj/18.7.1730 UR - http://dx.doi.org/10.1093/emboj/18.7.1730 ER - TY - JOUR AU - Chang, G. AU - Spencer, R. H. AU - Lee, A. T. AU - Barclay, M. T. AU - Rees, D. C. TI - Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel JO - Science PY - 1998/// VL - 282 SP - 2220 EP - 2226 M3 - 10.1126/science.282.5397.2220 N1 - 10.1126/science.282.5397.2220 UR - http://dx.doi.org/10.1126/science.282.5397.2220 ER - TY - JOUR AU - Ou, X. AU - Blount, P. AU - Hoffman, R. J. AU - Kung, C. TI - One face of a transmembrane helix is crucial in mechanosensitive channel gating JO - Proc. Natl Acad. Sci. USA PY - 1998/// VL - 95 SP - 11471 EP - 11475 M3 - 10.1073/pnas.95.19.11471 N1 - 10.1073/pnas.95.19.11471 UR - http://dx.doi.org/10.1073/pnas.95.19.11471 ER - TY - JOUR AU - Yoshimura, K. AU - Batiza, A. AU - Schroeder, M. AU - Blount, P. AU - Kung, C. TI - Hydrophilicity of a single residue residue within MscL correlates with increased channel mechanosensitivity JO - Biophys. J. PY - 1999/// VL - 77 SP - 1960 EP - 1972 ER - TY - JOUR AU - Yoshimura, K. AU - Batiza, A. AU - Kung, C. TI - Chemically charging the pore constriction opens the mechanosensitive channel MscL JO - Biophys. J. PY - 2001/// VL - 80 SP - 2198 EP - 2206 ER - TY - JOUR AU - Cruickshank, C. C. AU - Minchin, R. F. AU - Le Dain, A. C. AU - Martinac, B. TI - Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli JO - Biophys. J. PY - 1997/// VL - 73 SP - 1925 EP - 1931 ER - TY - JOUR AU - Spencer, R. H. AU - Chang, G. AU - Rees, D. C. TI - `Feeling the pressure': structural insights into a gated mechanosensitive channel JO - Curr. Opin. Struct. Biol. PY - 1999/// VL - 9 SP - 448 EP - 454 M3 - 10.1016/S0959-440X(99)80063-3 N1 - 10.1016/S0959-440X(99)80063-3 UR - http://dx.doi.org/10.1016/S0959-440X(99)80063-3 ER - TY - JOUR AU - Batiza, A. F. AU - Rayment, I. AU - Kung, C. TI - Channel gate: Tension, leak and disclosure JO - Struct. Fold. Design PY - 1999/// VL - 7 SP - R99 EP - R103 M3 - 10.1016/S0969-2126(99)80061-6 N1 - 10.1016/S0969-2126(99)80061-6 UR - http://dx.doi.org/10.1016/S0969-2126(99)80061-6 ER - TY - JOUR AU - Sukharev, S. AU - Betanzos, M. AU - Chiang, C.-S. AU - Guy, H. TI - The gating mechanism of the large mechanosensitive channel MscL JO - Nature PY - 2001/// VL - 409 SP - 720 EP - 724 M3 - 10.1038/35055559 N1 - 10.1038/35055559 UR - http://dx.doi.org/10.1038/35055559 ER - TY - JOUR AU - Sukharev, S. AU - Durell, S. R. AU - Guy, H. R. TI - Structural models of the MscL gating mechanism JO - Biophys. J. PY - 2001/// VL - 81 SP - 917 EP - 936 ER - TY - GEN PY - /// ER - TY - JOUR AU - Maingret, F. AU - Patel, A. J. AU - Lesage, F. AU - Lazdunski, M. AU - Honore, E. TI - Lysophospholipids open the two-pore domain mechano-gated K+ channels TREK-1 and TRAAK JO - J. Biol. Chem. PY - 2000/// VL - 275 SP - 10128 EP - 10133 M3 - 10.1074/jbc.275.14.10128 N1 - 10.1074/jbc.275.14.10128 UR - http://dx.doi.org/10.1074/jbc.275.14.10128 ER - TY - JOUR AU - Hubbell, W. L. AU - Gross, A. AU - Langen, R. AU - Lietzow, M. A. TI - Recent advances in site-directed spin labeling of proteins JO - Curr. Opin. Struct. Biol. PY - 1998/// VL - 8 SP - 649 EP - 656 M3 - 10.1016/S0959-440X(98)80158-9 N1 - 10.1016/S0959-440X(98)80158-9 UR - http://dx.doi.org/10.1016/S0959-440X(98)80158-9 ER - TY - JOUR AU - Hubbell, W. L. AU - Cafiso, D. S. AU - Altenbach, C. TI - Identifying conformational changes with site-directed spin labeling JO - Nature Struct. Biol. PY - 2000/// VL - 7 SP - 735 EP - 739 M3 - 10.1038/78956 N1 - 10.1038/78956 UR - http://dx.doi.org/10.1038/78956 ER - TY - GEN AU - Mchaourab, H. AU - Perozo, E. TI - Biological Magnetic Resonance PY - 2000/// VL - Vol. 19 ER - TY - JOUR AU - Perozo, E. AU - Kloda, A. AU - Cortes, D. M. AU - Martinac, B. TI - Site-directed spin-labeling analysis of reconstituted Mscl in the closed state JO - J. Gen. Physiol. PY - 2001/// VL - 118 SP - 193 EP - 206 M3 - 10.1085/jgp.118.2.193 N1 - 10.1085/jgp.118.2.193 UR - http://dx.doi.org/10.1085/jgp.118.2.193 ER - TY - JOUR AU - Sompornpisut, P. AU - Liu, Y. S. AU - Perozo, E. TI - Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations JO - Biophys. J. PY - 2001/// VL - 81 SP - 2530 EP - 2546 ER - TY - JOUR AU - Liu, Y. S. AU - Sompornpisut, P. AU - Perozo, E. TI - Structure of the KcsA channel intracellular gate in the open state JO - Nature Struct. Biol. PY - 2001/// VL - 8 SP - 883 EP - 887 M3 - 10.1038/nsb1001-883 N1 - 10.1038/nsb1001-883 UR - http://dx.doi.org/10.1038/nsb1001-883 ER - TY - JOUR AU - Lee, B. AU - Richards, F. M. TI - The interpretation of protein structures: estimation of static accessibility JO - J. Mol. Biol. PY - 1971/// VL - 55 SP - 379 EP - 400 ER - TY - JOUR AU - Martinac, B. AU - Buechner, M. AU - Delcour, A. H. AU - Adler, J. AU - Kung, C. TI - Pressure-sensitive ion channel in Escherichia coli JO - Proc. Natl Acad. Sci. USA PY - 1987/// VL - 84 SP - 2297 EP - 2301 ER - TY - JOUR AU - Martinac, B. TI - Mechanosensitive channels in prokaryotes JO - Cell Physiol. Biochem. PY - 2001/// VL - 11 SP - 61 EP - 76 M3 - 10.1159/000047793 N1 - 10.1159/000047793 UR - http://dx.doi.org/10.1159/000047793 ER - TY - JOUR AU - Gullingsrud, J. AU - Kosztin, D. AU - Schulten, K. TI - Structural determinants of MscL gating studied by molecular dynamics simulations JO - Biophys. J. PY - 2001/// VL - 80 SP - 2074 EP - 2081 ER - TY - JOUR AU - Smart, O. S. AU - Neduvelil, J. G. AU - Wang, X. AU - Wallace, B. A. AU - Sansom, M. S. TI - HOLE: a program for the analysis of the pore dimensions of ion channel structural models JO - J. Mol. Graph. PY - 1996/// VL - 14 SP - 354 EP - 360 M3 - 10.1016/S0263-7855(97)00009-X N1 - 10.1016/S0263-7855(97)00009-X UR - http://dx.doi.org/10.1016/S0263-7855(97)00009-X ER - TY - JOUR AU - Sukharev, S. I. AU - Sigurdson, W. J. AU - Kung, C. AU - Sachs, F. TI - Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL JO - J. Gen. Physiol. PY - 1999/// VL - 113 SP - 525 EP - 540 M3 - 10.1085/jgp.113.4.525 N1 - 10.1085/jgp.113.4.525 UR - http://dx.doi.org/10.1085/jgp.113.4.525 ER - TY - JOUR AU - Perozo, E. AU - Cortes, D. M. AU - Cuello, L. G. TI - Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy JO - Nature Struct. Biol. PY - 1998/// VL - 5 SP - 459 EP - 469 ER - TY - JOUR AU - Cortes, D. M. AU - Cuello, L. G. AU - Perozo, E. TI - Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating JO - J. Gen. Physiol. PY - 2001/// VL - 117 SP - 165 EP - 180 M3 - 10.1085/jgp.117.2.165 N1 - 10.1085/jgp.117.2.165 UR - http://dx.doi.org/10.1085/jgp.117.2.165 ER - TY - JOUR AU - Altenbach, C. AU - Marti, T. AU - Khorana, H. G. AU - Hubbell, W. L. TI - Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants JO - Science PY - 1990/// VL - 248 SP - 1088 EP - 1092 ER - TY - GEN AU - Abragam, A. TI - Principles of Nuclear Magnetism PY - 1961/// ER - TY - JOUR AU - Sompornpisut, P. AU - Mchaourab, H. AU - Perozo, E. TI - Spectroscopically-determined solvent accessibilities as constraints for global fold discrimination in proteins JO - Biophys. J. PY - 2002/// VL - 82 SP - 474a EP - 474a ER - TY - GEN AU - Case, D. A. PY - 1999/// ER - TY - JOUR AU - Laskowski, R. A. AU - Rullmannn, J. A. AU - MacArthur, M. W. AU - Kaptein, R. AU - Thornton, J. M. TI - AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR JO - J. Biomol. NMR PY - 1996/// VL - 8 SP - 477 EP - 486 ER - TY - JOUR AU - Nicholls, A. AU - Sharp, K. A. AU - Honig, B. TI - Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons JO - Proteins PY - 1991/// VL - 11 SP - 281 EP - 296 ER -