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Nature 418, 926-928 (29 August 2002) | doi:10.1038/418926a
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Apoptosis: Sculpture of a fly's head
Jun R. Huh & Bruce A. Hay
Abstract
Hox proteins are needed during development to produce body segments with different shapes and functions. In fruitflies, one Hox protein sculpts certain segments of the head by activating a cell-death-inducing gene.
Cell death occurs throughout the development of every animal, enabling excess cells to be eliminated, tissues to be sculpted, and cells or tissues that have outlived their usefulness to be removed1. Much of this death occurs by an active 'suicide' process known as apoptosis.
- Jun R. Huh and Bruce A. Hay are in the Division of Biology, MC156-29, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA.
Correspondence to: e-mail: Email: haybruce@its.caltech.edu
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