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Nature 418, 595-597 (8 August 2002) | doi:10.1038/418595a
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Obesity: Keeping hunger at bay
Michael W. Schwartz & Gregory J. Morton
Abstract
Many different hormones control our weight and appetite. The discovery of another hormone, which suppresses appetite for up to 12 hours, may lead to a better understanding of this complex control system.
Spurred on both by a series of remarkable discoveries and by the emergence of obesity as a world health problem, research into how our bodies control our appetite and weight continues at an unparalleled pace. The result is an increasingly clear insight into the workings of a fascinating but complex neuroendocrine system, in which circulating hormones convey information about energy balance (the difference between energy intake and expenditure) to brain pathways that control eating and energy output.
- Michael W. Schwartz and Gregory J. Morton are in the Division of Metabolism, Endocrinology and Nutrition, University of Washington and Harborview Medical Center, 325 9th Avenue, Seattle, Washington 98104-2499, USA.
Correspondence to: e-mail: Email: mschwart@u.washington.edu
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