Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 418, 594-595 (8 August 2002) | doi:10.1038/418594a
HIV: A tough viral nut to crack
Roger J. Pomerantz
Abstract
HIV cannot multiply in certain human cells unless it expresses a protein called Vif, the function of which has finally been revealed. It seems that it overcomes a human protein that would otherwise block viral replication.
Nowadays, researchers generally succeed in working out what viral proteins do within a few years of their discovery. This is certainly the case for nearly all proteins from the type 1 human immunodeficiency virus (HIV-1), whose genome is arguably the most extensively studied 9,700 or so bases of genetic sequence on the planet.
To read this story in full you will need to login or make a payment (see right).
