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Brief Communications
Nature 418, 497 (1 August 2002) | doi:10.1038/418497a
Open Innovation Challenges
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Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
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Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
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Postdoctoral Position in Cystic Fibrosis / Pulmonary Research
- Universitatsklinikum Heidelberg
- Heidelberg 69120 Germany
CERC in Developmental Immunology and Immunosenescence
- Dalhousie University
- Halifax, Nova Scotia
Oogenesis: Maturation of mouse fetal germ cells in vitro
Yayoi Obata1, Tomohiro Kono2 & Izuho Hatada1
Abstract
Even immature oocytes can eventually be fertilized after some skilful manipulation.
Abstract
Nuclear reprogramming is essential during gametogenesis for the production of totipotent zygotes. Here we show that premeiotic female germ cells derived from mouse fetuses as early as 12.5 days post coitum are able to complete meiosis and genomic imprinting in vitro and that these matured oocytes are highly competent in supporting development to full term after nuclear transfer and in vitro fertilization. To our knowledge, this is the first time that complete oogenesis has been successfully accomplished in vitro.
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