Figures and Tables

From the following article:

Short interfering RNA confers intracellular antiviral immunity in human cells

Leonid Gitlin, Sveta Karelsky and Raul Andino

Nature 418, 430-434(25 July 2002)

doi:10.1038/nature00873

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Figure 1

Poliovirus growth suppressed by siRNA.

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Figure 2

siRNA inhibits replication of poliovirus replicon in a sequence-dependent manner.

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Figure 3

Gene silencing is rapid, post-transcriptional, and not dependent on viral replication.

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Figure 4

Most cells treated with siC clear infection and do not harbour viral genomes.

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Figure 5

Infected cells survive more than a day, but are eventually lysed by emerging siRNA-resistant virus.

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