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Nature 418, 268-269 (18 July 2002) | doi:10.1038/418268a
Open Innovation Challenges
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Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
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Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
nature jobs
Head, Protein Production Unit
- The Novo Nordisk Foundation Center for Protein Research
- Copenhagen 2200 Denmark
Director
- The National Center for Complementary and Alternative Medicine (NCCAM)
- Bethesda, MD
Ion channel structures: They said it couldn't be done...
Alison Abbott1
Abstract
Determining the structure of cell-membrane ion channels was thought to be mission impossible. Alison Abbott meets the researcher who proved the doubters wrong, opening new windows on cellular function.
Rod MacKinnon woke up on 1 January 1998 with a sickening feeling that his eureka moment had been a dream. Late into the night, at Cornell University's synchrotron light source in Ithaca, New York, he had been processing data on the structure of a crystallized potassium-ion channel from a cell membrane.
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