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From the following article:

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli & Marco E. Bianchi

Nature 418, 191-195(11 July 2002)

doi:10.1038/nature00858

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Chromatin association of HMGB1 in living and dead HeLa cells.

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Figure 2

HMGB1 dynamics in living and apoptotic cells.

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Figure 3

Chromatin changes that occur in apoptosis create binding substrates for HMGB1.

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Figure 4

HMGB1 release promotes inflammatory responses.

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