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Nature 418, 29-30 (4 July 2002) | doi:10.1038/418029a

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Embryology: Fluid flow and broken symmetry

Claudio D. Stern

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The asymmetries between the right- and left-hand sides of the body are initiated at an early stage of development. Two groups provide welcome news of progress in revealing the mechanism concerned and its generality.

How an embryo first distinguishes its left from its right side has baffled embryologists for a long time. The rotational beating of cilia — hair-like structures attached to individual cells — is known to be essential for the process.