Table of contents
Volume 417 Number 6889 pp3-672
Naturejobs
ProspectsLanding the egos p3
Paul Smaglik
doi:10.1038/nj6889-03a
regions
Seattle: The best of both worlds p4
Paul Smaglik
doi:10.1038/nj6889-04a
Opinion
Genomics and taxonomy for all p573
Principles of access to public and private databases are often contentious, and a proposal in this issue will no doubt spark more debate. Meanwhile, Nature is taking a small step towards a database for taxonomists.
doi:10.1038/417573a
Remove barricades! Preserve culture! p573
Congratulations to French publications for their pragmatic approach to language. Other institutions should follow suit.
doi:10.1038/417573b
News
Alpine detector fails to confirm Italian sighting of dark matter p575
Alison Abbott
doi:10.1038/417575a
Supreme Court closes loophole for copycat patents p575
Jonathan Knight
doi:10.1038/417575b
South African cabinet backs merger plan for universities p576
Michael Cherry
doi:10.1038/417576a
Chinese researcher accused of stealing cell samples p576
Rex Dalton
doi:10.1038/417576b
World Bank cracks down on cultural damage p577
Rex Dalton
doi:10.1038/417577a
British science champion quits post p577
David Adam
doi:10.1038/417577b
Uncertainty ends for US nuclear lab as new leader is named p577
Rex Dalton
doi:10.1038/417577c
Ecologist sues over wrecked iguana study p578
John Whitfield
doi:10.1038/417578a
Merger plans rattle bones in Berlin p578
Johanna Schwarz
doi:10.1038/417578b
Joint projects see ocean science aiming high p579
Mark Schrope
doi:10.1038/417579a
US postal service puts anthrax detectors to the test p579
Jonathan Knight
doi:10.1038/417579b
news feature
Pilotless research aircraft: Flying free p582
Pilotless aircraft could help monitor forest fires, or collect data over vast areas of ocean. But aviation authorities are reluctant to let them share the sky with other aircraft. Tom Clarke reports.
Tom Clarke
doi:10.1038/417582a
Therapeutic antibodies: Magic bullets hit the target p584
After decades of disappointment, antibodies are finally emerging as viable — if expensive — drugs. Trisha Gura finds biotech start-ups and pharmaceutical giants rushing to claim a piece of the action.
Trisha Gura
doi:10.1038/417584a
Correspondence
Knowledge about animal suffering is too rarely used p587
Researchers in different fields should pool information to minimize unnecessary harm.
Andrew N. Rowan
doi:10.1038/417587a
Conceptual biology: a semantic issue and more p587
Julie C. Barnes
doi:10.1038/417587b
Uncovering the complex mysteries of mosaicism p588
Tayfun Özçelik
doi:10.1038/417588a
Bioinformatics code must enforce citation p588
David J. States
doi:10.1038/417588b
Commentary
The times they are a-changin' p589
Policies on release of biological data should reflect reality, to the benefit of all.
doi:10.1038/417589a
Book Reviews
Lateral thinking p591
A handy guide shows that there's more to left and right than meets the eye.
William D. Hopkins reviews Right Hand, Left hand: The Origins of Asymmetry in Brains, Bodies, Atoms and Cultures by Chris McManus
doi:10.1038/417591a
Controlling a generous host p592
Paul Schmid-Hempel reviews Parasites and the Behavior of Animals by Janice Moore
doi:10.1038/417592a
Tripping the light fantastic p592
doi:10.1038/417592b
Exploiting a hostile world p593
Lynn J. Rothschild reviews Life at the Limits: Organisms in Extreme Environments by David A. Wharton
doi:10.1038/417593a
New Journals p593
doi:10.1038/417593b
News and Views
Atmospheric chemistry: Iodine's air of importance p597
Iodine-containing emissions from marine algae can be converted by sunlight into aerosol particles. If this phenomenon occurs on a large scale, it could have significant effects on climate.
Charles E. Kolb
doi:10.1038/417597a
Developmental genetics: Buffer zone p598
Heat-shock proteins help to protect organisms from external stresses. The idea that they can also buffer against internal — genetic — variations has received support from studies of fruitflies and, now, of plants.
Massimo Pigliucci
doi:10.1038/417598a
Condensed-matter physics: Indirect evidence p599
The ease with which electrons move through some metals depends on which direction they take. Watching electrons move along metal planes gives new insight, curiously, into how they move between them.
Andrew Millis
doi:10.1038/417599a
Neurobiology: Glutamate receptors on the move p601
Receptors for the neurotransmitter glutamate are more mobile than previously suspected. They meander about on the neuronal surface and become reversibly trapped at the junctions between neurons.
Morgan Sheng and Terunaga Nakagawa
doi:10.1038/417601a
100 and 50 years ago p602
doi:10.1038/417602a
Astronomy: The Hoyle story p603
The achievements of Fred Hoyle, one of the twentieth century's great innovators in astronomy, were celebrated at a recent meeting. In many respects, it emerged, Hoyle's thinking was ahead of his time.
John Maddox
doi:10.1038/417603a
Earth science: African reflections p603
Tim Lincoln
doi:10.1038/417603b
Developmental neurobiology: Cortical liars p605
Inhibitory cells known as interneurons constitute a significant proportion of the neurons in the neocortex of mammalian brains. As far as interneuron origins are concerned, humans may be the odd man out.
Seong-Seng Tan
doi:10.1038/417605a
Daedalus: Toughened metal p606
David Jones
doi:10.1038/417606a
Brief Communications
Galapagos Islands: Marine iguanas die from trace oil pollution p607
A near-miss ecological disaster still left a sinister aftermath for these giant lizards.
Martin Wikelski, Vanessa Wong, Brett Chevalier, Niels Rattenborg and Howard L. Snell
doi:10.1038/417607a
First paragraph | Full Text | PDF (115K)
Ecology: Darwin's naturalization hypothesis challenged p608
Richard P. Duncan and Peter A. Williams
doi:10.1038/417608a
First paragraph | Full Text | PDF (125K)
Palaeobiology: Calcification of early vertebrate cartilage p609
Philippe Janvier and Marius Arsenault
doi:10.1038/417609a
First paragraph | Full Text | PDF (128K)
Microbial evolution (Communication arising): Antitoxin vaccines and pathogen virulence p609
Benoit Soubeyrand and Stanley A. Plotkin
doi:10.1038/417609b
First paragraph | Full Text | PDF (128K)
Microbial evolution (Communication arising): Antitoxin vaccines and pathogen virulence p610
Sylvain Gandon, Margaret J. Mackinnon, Sean Nee and Andrew F. Read
doi:10.1038/417610a
First paragraph | Full Text | PDF (41K)
Review
Computational and evolutionary aspects of language p611
Martin A. Nowak, Natalia L. Komarova and Partha Niyogi
doi:10.1038/nature00771
Abstract | Full Text | PDF (228K)
Article
Hsp90 as a capacitor of phenotypic variation p618
Christine Queitsch, Todd A. Sangster and Susan Lindquist
doi:10.1038/nature749
Abstract | Full Text | PDF (561K) | Supplementary information
See also: News and Views by Pigliucci
Letters to Nature
Observational evidence for the accretion-disk origin for a radio jet in an active galaxy p625
Alan P. Marscher, Svetlana G. Jorstad, José-Luis Gómez, Margo F. Aller, Harri Teräsranta, Matthew L. Lister and Alastair M. Stirling
doi:10.1038/nature00772
First paragraph | Full Text | PDF (543K)
Coherence–incoherence and dimensional crossover in layered strongly correlated metals p627
T. Valla, P. D. Johnson, Z. Yusof, B. Wells, Q. Li, S. M. Loureiro, R. J. Cava, M. Mikami, Y. Mori, M. Yoshimura and T. Sasaki
doi:10.1038/nature00774
First paragraph | Full Text | PDF (275K)
See also: News and Views by Millis
Measurement of a confinement induced neutron phase p630
H. Rauch, H. Lemmel, M. Baron and R. Loidl
doi:10.1038/nature00773
First paragraph | Full Text | PDF (187K)
Marine aerosol formation from biogenic iodine emissions p632
Colin D. O'Dowd, Jose L. Jimenez, Roya Bahreini, Richard C. Flagan, John H. Seinfeld, Kaarle Hämeri, Liisa Pirjola, Markku Kulmala, S. Gerard Jennings and Thorsten Hoffmann
doi:10.1038/nature00775
First paragraph | Full Text | PDF (373K)
See also: News and Views by Kolb
Biodiversity as a barrier to ecological invasion p636
Theodore A. Kennedy, Shahid Naeem, Katherine M. Howe, Johannes M. H. Knops, David Tilman and Peter Reich
doi:10.1038/nature00776
First paragraph | Full Text | PDF (502K)
Plant biomarkers in aerosols record isotopic discrimination of terrestrial photosynthesis p639
Maureen H. Conte and John C. Weber
doi:10.1038/nature00777
First paragraph | Full Text | PDF (268K)
Host-induced epidemic spread of the cholera bacterium p642
D. Scott Merrell, Susan M. Butler, Firdausi Qadri, Nadia A. Dolganov, Ahsfaqul Alam, Mitchell B. Cohen, Stephen B. Calderwood, Gary K. Schoolnik and Andrew Camilli
doi:10.1038/nature00778
First paragraph | Full Text | PDF (217K) | Supplementary information
Origin of GABAergic neurons in the human neocortex p645
Kresimir Letinic, Roberto Zoncu and Pasko Rakic
doi:10.1038/nature00779
First paragraph | Full Text | PDF (513K)
See also: News and Views by Tan
Regulation of AMPA receptor lateral movements p649
Aren J. Borgdorff and Daniel Choquet
doi:10.1038/nature00780
First paragraph | Full Text | PDF (491K) | Supplementary information
See also: News and Views by Sheng & Nakagawa
Annexin II light chain regulates sensory neuron-specific sodium channel expression p653
Kenji Okuse, Misbah Malik-Hall, Mark D. Baker, W-Y. Louisa Poon, Haeyoung Kong, Moses V. Chao and John N. Wood
doi:10.1038/nature00781
First paragraph | Full Text | PDF (373K) | Supplementary information
Filamentous phage integration requires the host recombinases XerC and XerD p656
Kathryn E. Huber and Matthew K. Waldor
doi:10.1038/nature00782
First paragraph | Full Text | PDF (354K)
A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans p660
Sarah L. Crittenden, David S. Bernstein, Jennifer L. Bachorik, Beth E. Thompson, Maria Gallegos, Andrei G. Petcherski, Gary Moulder, Robert Barstead, Marvin Wickens and Judith Kimble
doi:10.1038/nature754
First paragraph | Full Text | PDF (483K)
Kremen proteins are Dickkopf receptors that regulate Wnt/
-catenin signalling p664
Bingyu Mao, Wei Wu, Gary Davidson, Joachim Marhold, Mingfa Li, Bernard M. Mechler, Hajo Delius, Dana Hoppe, Peter Stannek, Carmen Walter, Andrei Glinka and Christof Niehrs
doi:10.1038/nature756
First paragraph | Full Text | PDF (536K)
New components of the spliced leader RNP required for nematode trans-splicing p667
John A. Denker, David M. Zuckerman, Patricia A. Maroney and Timothy W. Nilsen
doi:10.1038/nature00783
First paragraph | Full Text | PDF (332K) | Supplementary information
New on the Market
DNA and protein microarrays p671
Microarrays are everywhere, doing everything...
doi:10.1038/417671a