Access

News and Views

Nature 417, 605-606 (6 June 2002) | doi:10.1038/417605a

Open Innovation Challenges

naturejobs

Developmental neurobiology: Cortical liars

Seong-Seng Tan

Top

Inhibitory cells known as interneurons constitute a significant proportion of the neurons in the neocortex of mammalian brains. As far as interneuron origins are concerned, humans may be the odd man out.

For more than a decade, the interneurons found in the neocortex of the human brain have been disturbing the peace of developmental neurobiologists. Interneurons represent roughly 20% of cortical neurons and are responsible for modulating the firing of the principal neurons known as projection neurons.