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Nature 417, 494-497 (30 May 2002) | doi:10.1038/417494a

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Cell motility: Sharks' teeth and dunes

Laura M. Machesky

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In order to move, cells need to push out protrusions known as lamellipods. These can vary greatly in their shapes, dynamics and contributions to motility, depending on their underlying molecular architecture.

What does it take to make a cell move? You might think that after more than 50 years of study, we could form a reasonable answer to this question.