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Nature 417, 387-388 (23 May 2002) | doi:10.1038/417387a
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Research Fellows - Nanotechnology and Nanobiotechnology
- Amrita Institute of Medical Sciences & Research Centre (AIMS)
- Kochi, Kerala 682 026 India
Forest Insect Ecologists
- Natural Resources Canada Canadian Forest Service (CFS)
- Fredericton, New Brunswick, Canada
Medicine: Anti-malarial mosquitoes?
Gareth J. Lycett1 & Fotis C. Kafatos1
Abstract
Researchers have generated genetically altered mosquitoes with a reduced ability to transmit the malaria parasite in the lab. This is an important proof of principle, but there's still a long road ahead.
Ever since molecular biologists discovered how to genetically transform fruitflies, malaria researchers have dreamt about using similar techniques to turn disease-carrying mosquitoes into harmless pests. If such 'transgenic' mosquitoes were genetically fit but unable to transmit the malaria-causing parasite, Plasmodium falciparum, and if they could be introduced into natural populations at a high enough frequency, they might reduce the prevalence of this disease.
- Gareth J. Lycett and Fotis C. Kafatos are in the European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
e-mails: Email: lycett@embl-heidelberg.de; Email: dg-office@embl-heidelberg.de
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