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Nature 417, 343-350 (16 May 2002) | doi:10.1038/417343a
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Faculty - Plant Cellular & Molecular Biology, Molecular Genetics & the Plant Molecular Biology / Biotechnology Program
- The Ohio State University
- Columbus, Ohio
Endowed Professorship
- Washington University School of Medicine in St. Louis
- St. Louis, MO 63110 United States
review article A small-systems approach to motor pattern generation
Michael P. Nusbaum & Mark P. Beenhakker
Abstract
How neuronal networks enable animals, humans included, to make coordinated movements is a continuing goal of neuroscience research. The stomatogastric nervous system of decapod crustaceans, which contains a set of distinct but interacting motor circuits, has contributed significantly to the general principles guiding our present understanding of how rhythmic motor circuits operate at the cellular level. This results from a detailed documentation of the circuit dynamics underlying motor pattern generation in this system as well as its modulation by individual transmitters and neurons.
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