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Nature 416, 865-869 (25 April 2002) | doi:10.1038/416865a;
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Scientist / Sr. Scientist - Biopharmaceutics
- Syngene International
- Bangalore, Karnataka 560099 India
Tier II Canada Research Chair in Cellular Science and Human Health
- Concordia University
- Montreal, Quebec Canada
Increased proliferation of B cells and auto-immunity in mice lacking protein kinase C|[delta]|
Protein kinase C (PKC), which comprises 11 closely related isoforms, has been implicated in a wide variety of cellular processes, such as growth, differentiation, secretion, apoptosis and tumour development. Among the PKC isotypes, PKC-|[delta]| is unique in that its overexpression results in inhibition of cell growth.
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