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Nature 416, 636-640 (11 April 2002) | doi:10.1038/416636a;
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Chondroitinase ABC promotes functional recovery after spinal cord injury
The inability of axons to regenerate after a spinal cord injury in the adult mammalian central nervous system (CNS) can lead to permanent paralysis. At sites of CNS injury, a glial scar develops, containing extracellular matrix molecules including chondroitin sulphate proteoglycans (CSPGs).
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