Table of contents
Volume 416 Number 6881 pp3-662
Naturejobs
ProspectsReinventing careers p3
Paul Smaglik
doi:10.1038/nj6881-03a
regions
Vienna: Empire building p4
Paul Smaglik
doi:10.1038/nj6881-04a
Opinion
Rice must be perfectly cooked p567
The draft genome sequences of Oryza sativa, published last week, are impressive achievements, but not the finished article. The public rice genome project more than ever deserves support.
doi:10.1038/416567a
A climate for change p567
US climate research faces a revamp that may provide political leaders with better scientific information. Will they listen?
doi:10.1038/416567b
News
Ranches blamed over spread of mad deer p569
Jonathan Knight
doi:10.1038/416569a
Smithsonian rocked by high-level departure p569
Josette Chen
doi:10.1038/416569b
Disbelief greets claim for creation of first human clone p570
Alison Abbott
doi:10.1038/416570a
Court rules out Italian research appointment p570
Sally Goodman
doi:10.1038/416570b
Stream of escaped farm fish raises fears for wild salmon p571
Natasha McDowell
doi:10.1038/416571a
White House plans to increase 'relevance' of climate research p571
Mark Schrope
doi:10.1038/416571b
Chinese institute is an innovation in theory p572
David Cyranoski
doi:10.1038/416572a
US strikes a deal on export rules p572
Tony Reichhardt
doi:10.1038/416572b
Rice genome sequencers cook up merger p573
Declan Butler
doi:10.1038/416573a
Government warned over future of cash-starved labs p573
David Adam
doi:10.1038/416573b
news feature
Agricultural biotech: The rice squad p576
Feeding the world in the twenty-first century could require a second green revolution. But that may involve the most audacious feat of genetic engineering yet attempted, says Christopher Surridge.
Christopher Surridge
doi:10.1038/416576a
Computer modelling: Our virtual planet p579
Japan's Earth Simulator supercomputer could provide the most accurate models yet of the planet's climate and geophysics — but there are obstacles to realizing that potential. Robert Triendl reports.
Robert Triendl
doi:10.1038/416579a
Correspondence
How affluence could be good for the environment p581
Intensive farming means the United States uses less land to feed more people than ever.
Stephen Budiansky
doi:10.1038/416581a
Training to think globally p581
Franklin Huang and Matt Stremlau
doi:10.1038/416581b
Hamilton built on work by Haldane and Fisher p581
A. W. F. Edwards
doi:10.1038/416581c
Book Reviews
Thoughts of a rationalist p583
Provocative ideas about science from a reductionist viewpoint.
John Polkinghorne reviews Facing Up: Science and Its Cultural Adversaries by Steven Weinberg
doi:10.1038/416583a
New Journals p583
doi:10.1038/416583b
Flights of fancy p584
doi:10.1038/416584a
It's not all in the genes p584
Ralph Tollrian reviews Phenotypic Plasticity: Beyond Nature and Nurture by Massimo Pigliucci
doi:10.1038/416584b
Science in culture p585
Roald Hoffmann and Sylvie Coyaud review
doi:10.1038/416585a
concepts
Chemical synthesis: The art of chemistry p587
Success in the synthesis of natural products often requires the ability to react a single part of a molecule to the exclusion of others.
Stephen J. Lippard
doi:10.1038/416587a
News and Views
Medicine: Clearing a path for nerve growth p589
After spinal-cord injury, severed nerve fibres face a thicket of obstacles as they try to regenerate. Researchers have used a bacterial enzyme to help prune these obstacles in rats.
Lars Olson
doi:10.1038/416589a
Plant biology: The first harvest of crop genes p590
Draft sequences of the rice genome have been produced by two groups. The drafts will be an invaluable resource for research on the genomes of other plants, the cereals in particular.
Michael Bevan
doi:10.1038/416590a
Geophysics: The disappearing dipole p591
Satellite measurements of the Earth's magnetic field reveal a detailed picture of the circulation in the liquid iron core. The data suggest that the planet could be in the early stages of reversing its magnetic polarity.
Peter Olson
doi:10.1038/416591a
Molecular biology: Alternative arrays p593
Richard Turner
doi:10.1038/416593a
100 and 50 years ago p594
doi:10.1038/416594a
Global change: Carbon dioxide goes with the flow p594
Measurements of the rate at which carbon dioxide is released from rivers running through tropical forests provide a surprise. They will help in developing an improved picture of the carbon cycle.
John Grace and Yadvinder Malhi
doi:10.1038/416594b
Immunology: DNA drives autoimmunity p595
In autoimmune diseases, a person's tissues are destroyed by their own immune system. IgG, a normal component of blood, provokes autoimmune responses when immune cells recognize it as a complex with DNA.
Carola G. Vinuesa and Christopher C. Goodnow
doi:10.1038/416595a
Astronomy: The wanderer returns p597
Tom Clarke
doi:10.1038/416597a
Daedalus: Meteoric heating p598
David Jones
doi:10.1038/416598a
Brief Communications
Herbivory: Caterpillar saliva beats plant defences p599
A new weapon emerges in the evolutionary arms race between plants and herbivores.
Richard O. Musser, Sue M. Hum-Musser, Herb Eichenseer, Michelle Peiffer, Gary Ervin, J. Brad Murphy and Gary W. Felton
doi:10.1038/416599a
First paragraph | Full Text | PDF (242K)
Biodiversity
Biodiversity (Communications arising): Suspect evidence of transgenic contamination (see editorial footnote) p600
Matthew Metz and Johannes Fütterer
doi:10.1038/nature738
First paragraph | Full Text | PDF (206K)
Biodiversity (Communications arising): Maize transgene results in Mexico are artefacts (see editorial footnote) p601
Nick Kaplinsky, David Braun, Damon Lisch, Angela Hay, Sarah Hake and Michael Freeling
doi:10.1038/nature739
First paragraph | Full Text | PDF (45K)
correction p602
doi:10.1038/416602b
Biodiversity (Communications arising (reply)): Suspect evidence of transgenic contamination/Maize transgene results in Mexico are artefacts (see editorial footnote) p602
David Quist and Ignacio H. Chapela
doi:10.1038/nature740
First paragraph | Full Text | PDF (48K)
Article
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors p603
Elizabeth A. Leadbetter, Ian R. Rifkin, Andreas M. Hohlbaum, Britte C. Beaudette, Mark J. Shlomchik and Ann Marshak-Rothstein
doi:10.1038/416603a
Abstract | Full Text | PDF (290K)
See also: News and Views by Vinuesa & Goodnow
Letters to Nature
Scaling of entanglement close to a quantum phase transition p608
A. Osterloh, Luigi Amico, G. Falci and Rosario Fazio
doi:10.1038/416608a
First paragraph | Full Text | PDF (320K)
Spontaneous breaking of time-reversal symmetry in the pseudogap state of a high-Tc superconductor p610
A. Kaminski, S. Rosenkranz, H. M. Fretwell, J. C. Campuzano, Z. Li, H. Raffy, W. G. Cullen, H. You, C. G. Olson, C. M. Varma and H. Höchst
doi:10.1038/416610a
First paragraph | Full Text | PDF (357K)
Optical studies of solid hydrogen to 320 GPa and evidence for black hydrogen p613
Paul Loubeyre, Florent Occelli and René LeToullec
doi:10.1038/416613a
First paragraph | Full Text | PDF (719K)
Outgassing from Amazonian rivers and wetlands as a large tropical source of atmospheric CO2 p617
Jeffrey E. Richey, John M. Melack, Anthony K. Aufdenkampe, Victoria M. Ballester and Laura L. Hess
doi:10.1038/416617a
First paragraph | Full Text | PDF (619K)
See also: News and Views by Grace & Malhi
Small-scale structure of the geodynamo inferred from Oersted and Magsat satellite data p620
Gauthier Hulot, Céline Eymin, Benoît Langlais, Mioara Mandea and Nils Olsen
doi:10.1038/416620a
First paragraph | Full Text | PDF (2,661K)
See also: News and Views by Olson
Strong male-driven evolution of DNA sequences in humans and apes p624
Kateryna D. Makova and Wen-Hsiung Li
doi:10.1038/416624a
First paragraph | Full Text | PDF (279K) | Supplementary information
Future projections for Mexican faunas under global climate change scenarios p626
A. Townsend Peterson, Miguel A. Ortega-Huerta, Jeremy Bartley, Victor Sánchez-Cordero, Jorge Soberón, Robert H. Buddemeier and David R. B. Stockwell
doi:10.1038/416626a
First paragraph | Full Text | PDF (345K)
Extraction of a weak climatic signal by an ecosystem p629
Arnold H. Taylor, J. Icarus Allen and Paul A. Clark
doi:10.1038/416629a
First paragraph | Full Text | PDF (338K)
Direct visuomotor transformations for reaching p632
Christopher A. Buneo, Murray R. Jarvis, Aaron P. Batista and Richard A. Andersen
doi:10.1038/416632a
First paragraph | Full Text | PDF (784K)
Chondroitinase ABC promotes functional recovery after spinal cord injury p636
Elizabeth J. Bradbury, Lawrence D. F. Moon, Reena J. Popat, Von R. King, Gavin S. Bennett, Preena N. Patel, James W. Fawcett and Stephen B. McMahon
doi:10.1038/416636a
First paragraph | Full Text | PDF (399K)
See also: News and Views by Olson
The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein p640
Marie Gottar, Vanessa Gobert, Tatiana Michel, Marcia Belvin, Geoffrey Duyk, Jules A. Hoffmann, Dominique Ferrandon and Julien Royet
doi:10.1038/nature734
First paragraph | Full Text | PDF (358K)
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli p644
Mika Rämet, Pascal Manfruelli, Alan Pearson, Bernard Mathey-Prevot and R. Alan B. Ezekowitz
doi:10.1038/nature735
First paragraph | Full Text | PDF (466K) | Supplementary information
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization p648
Muyang Li, Delin Chen, Ariel Shiloh, Jianyuan Luo, Anatoly Y. Nikolaev, Jun Qin and Wei Gu
doi:10.1038/nature737
First paragraph | Full Text | PDF (429K) | Supplementary information
Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays p653
Finny G. Kuruvilla, Alykhan F. Shamji, Scott M. Sternson, Paul J. Hergenrother and Stuart L. Schreiber
doi:10.1038/416653a
First paragraph | Full Text | PDF (368K) | Supplementary information
A 'periodic table' for protein structures p657
William R. Taylor
doi:10.1038/416657a
First paragraph | Full Text | PDF (364K) | Supplementary information
correction: Transition of Mount Etna lavas from a mantle-plume to an island-arc magmatic source p660
Pierre Schiano, Roberto Clocchiatti, Luisa Ottolini and Tiziana Busà
doi:10.1038/416660a
New on the Market
The discovery channel p661
Drug discovery — or at least supplying kit to do it with — is big business.
doi:10.1038/416661a