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Nature ${rb.getVolume()}, 624-626 (11 April 2002) | doi:10.1038/416624a;
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Strong male-driven evolution of DNA sequences in humans and apes
Studies of human genetic diseases have suggested a higher mutation rate in males than in females and the male-to-female ratio (α) of mutation rate has been estimated from DNA sequence and microsatellite data to be about 4–6 in higher primates. Two recent studies, however, claim that α is only about 2 in humans.
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