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Nature 416, 481 (4 April 2002) | doi:10.1038/416481a
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Toxicology: A risky business
Marcello Lotti1 & Pierluigi Nicotera2
Abstract
Toxicology research should urgently appraise its performance and join mainstream biomedical science.
Several key advances in biology and medicine in the past were brought about by studies of poisons. The eludication of the mechanism of carbon monoxide toxicity by Claude Bernard, which led to the understanding of the function of haemoglobin, is a classic example.
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