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Neurobiology

Serotonin sustains serenity

Nature volume 416, pages 377–379 (2002)Cite this article

An elegant variation on conventional gene-knockout techniques can delete a gene at specific times and locations in mice. The approach shows when and where a serotonin receptor protein is needed during development.

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Figure 1: Over-anxious mice.

R. HEN/S. RAMBOZ, MODIFIED

References

  1. Gross, C. et al. Nature 416, 396–400 (2002).

    Article  CAS  ADS  Google Scholar 

  2. Parks, C. L., Robinson, P. S., Sibille, E., Shenk, T. & Toth, M. Proc. Natl Acad. Sci. USA 95, 10734–10739 (1998).

    Article  CAS  ADS  Google Scholar 

  3. Ramboz, S. et al. Proc. Natl Acad. Sci. USA 95, 14476–14481 (1998).

    Article  CAS  ADS  Google Scholar 

  4. Heisler, L. K. et al. Proc. Natl Acad. Sci. USA 95, 15049–15054 (1998).

    Article  CAS  ADS  Google Scholar 

  5. D' Amato, R. J. et al. Proc. Natl Acad. Sci. USA 84, 4322–4326 (1987).

    Article  ADS  Google Scholar 

  6. Heim, C. & Nemeroff, C. B. Biol. Psychiatry 49, 1023–1039 (2001).

    Article  CAS  Google Scholar 

  7. Yan, W., Wilson, C. C. & Haring, J. H. Brain Res. Dev. Brain Res. 98, 185–190 (1997).

    Article  CAS  Google Scholar 

Download references

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  1. Departments of Neuroscience, Pharmacology and Molecular Science and Psychiatry, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, 21205, Maryland, USA

    Solomon H. Snyder

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  1. Solomon H. Snyder
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Correspondence to Solomon H. Snyder.

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Snyder, S. Serotonin sustains serenity. Nature 416, 377–379 (2002). https://doi.org/10.1038/416377a

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