Naturejobs

Translating words into action p3

Paul Smaglik

doi:10.1038/nj6877-03a

Full Text | PDF (80K)

Applications matter p4

Basic research in condensed-matter physics continues to lose ground to focused R&D. Effective cross-disciplinary partnering between universities, government labs and industry is seen as essential to the future health of basic research in this field. Brendan Horton explores.

Brendan Horton

doi:10.1038/nj6877-04a

Full Text | PDF (111K)

Slim pickings for silicon specialists p6

Electronics companies in Japan are slashing jobs for silicon physicists — once the veritable élite of the country's corporate R&D world. And public-sector research is only slowly picking up, says Robert Triendl.

Robert Triendl

doi:10.1038/nj6877-06a

Full Text | PDF (146K)

Opinion

Beyond the cloning debate p109

Arguments over human embryonic stem cells and cloning have loomed large over the choice of a new director of the National Institutes of Health. But the expected nominee for the position will need to prove himself on other fronts.

doi:10.1038/416109a

Full Text | PDF (44K)

Helping hands for Arab science p109

A grassroots initiative to boost research in the Middle East deserves support — in particular from Arab Americans.

doi:10.1038/416109b

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News

Geneticists get steamed up over public access to rice genome p111

Declan Butler

doi:10.1038/416111a

Full Text | PDF (202K)

Societies query student-visa review p111

Geoff Brumfiel

doi:10.1038/416111b

Full Text | PDF (202K)

NASA urged to play waiting game on Hubble's retirement p112

Tony Reichhardt

doi:10.1038/416112a

Full Text | PDF (114K)

Radiologist in the picture for top job at NIH p113

Erika Check

doi:10.1038/416113a

Full Text | PDF (76K)

Ecologists seek sustainable future p113

Rex Dalton

doi:10.1038/416113b

Full Text | PDF (76K)

Manchester merger to spawn research giant p114

David Adam

doi:10.1038/416114a

Full Text | PDF (203K)

Physicists set sights on exotic prey p114

Sally Goodman

doi:10.1038/416114b

Full Text | PDF (203K)

Genomics firm aims to fill Asian gene gap p115

David Cyranoski

doi:10.1038/416115a

Full Text | PDF (167K)

Formidable catalogue puts army of ants online p115

Tom Clarke

doi:10.1038/416115b

Full Text | PDF (167K)

news in brief p116

doi:10.1038/416116a

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news feature

Neutrino physics: Picking up the pieces p118

Last November, a shock wave crippled Japan's Super-Kamiokande neutrino detector. David Cyranoski and Geoff Brumfiel find out how physicists plan to resurrect the device.

David Cyranoski and Geoff Brumfiel

doi:10.1038/416118a

Full Text | PDF (453K)

Arab science: Blooms in the desert p120

The Arab world has a proud history of scholarship, but in recent decades it has neglected science. Now, against a backdrop of turmoil, a grassroots initiative hopes to restore the balance. Ehsan Masood reports.

Ehsan Masood

doi:10.1038/416120a

Full Text | PDF (181K)

Correspondence

In risk assessment, one has to admit ignorance p123

Explaining there are things we can't know could improve public confidence in science.

Holger Hoffmann-Riem and Brian Wynne

doi:10.1038/416123a

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Favouritism in physics? p123

Federico Rosei

doi:10.1038/416123b

Full Text | PDF (40K)

Book Reviews

Lots of peanut shells but no elephant p125

A controversial account of the discovery of HIV.

Jaap Goudsmit reviews Science Fictions: A Scientific Mystery, a Massive Cover-up, and the Dark Legacy of Robert Gallo by John Crewdson

doi:10.1038/416125a

Full Text | PDF (188K)

Bare bones of a life p126

C. K. Brain reviews Dart: Scientist and Man of Grit by Frances Wheelhouse and Kathaleen S. Smithford

doi:10.1038/416126a

Full Text | PDF (188K)

The shape of things to come p127

Dougal Dixon reviews Future Evolution: An Illuminated History of Life to Come by Peter Ward and Alexis Rockman

doi:10.1038/416127a

Full Text | PDF (160K)

concepts

Grammar: The barest essentials p129

Massimo Piattelli-Palmarini

doi:10.1038/416129a

Full Text | PDF (53K)

News and Views

Developmental biology: Senseless motion p131

Rhythmic movements such as locomotion are produced by oscillatory circuits in the central nervous system. Work in fruitflies shows that the neural circuitry for such movements develops without peripheral sensory feedback.

Eve Marder

doi:10.1038/416131a

Full Text | PDF (112K)

100 and 50 years ago p132

doi:10.1038/416132a

Full Text | PDF (126K)

Cosmology: Maintaining the standard p132

Cosmologists continue to probe for weaknesses in the 'standard model' for explaining the structure of the Universe. Happily, the model passes the latest observational test of its consistency.

George F. R. Ellis

doi:10.1038/416132b

Full Text | PDF (126K)

Signal transduction: Molecular ticket to enter cells p133

Just as important as starting cellular signalling pathways is switching them off again. It seems that the Cbl protein has a dual function in accelerating the degradation of certain signalling molecules.

Shlomo Oved and Yosef Yarden

doi:10.1038/416133a

Full Text | PDF (191K)

Oceanography: An extra dimension to mixing p136

According to a new theory, stratification of the oceans is controlled by a balance between heat input at the surface and heat redistribution by eddies. But it is early days for this sea-change in thinking.

Chris W. Hughes

doi:10.1038/416136a

Full Text | PDF (177K)

Neurobiology: The bitter-sweet taste of amino acids p136

Lesley Anson

doi:10.1038/416136b

Full Text | PDF (177K)

Cell biology: A new view of photoreceptors p139

The light-gathering structures in our eyes are specialized membranes found on cells known as photoreceptors. Two studies show that a protein called Crumbs is crucial for the development of these membranes.

Franck Pichaud and Claude Desplan

doi:10.1038/416139a

Full Text | PDF (192K)

Daedalus: Electric waves p140

David Jones

doi:10.1038/416140a

Full Text | PDF (139K)

Brief Communications

Brain-machine interface: Instant neural control of a movement signal p141

Hands-free operation of a cursor can be achieved by a few neurons in the motor cortex.

Mijail D. Serruya, Nicholas G. Hatsopoulos, Liam Paninski, Matthew R. Fellows and John P. Donoghue

doi:10.1038/416141a

First paragraph | Full Text | PDF (85K) | Supplementary information

Sonography: Dizygotic twin survival in early pregnancy p142

Stephen Tong, Simon Meagher and Beverley Vollenhoven

doi:10.1038/416142a

First paragraph | Full Text | PDF (63K)

Article

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis p143

Milena Pellikka, Guy Tanentzapf, Madalena Pinto, Christian Smith, C. Jane McGlade, Donald F. Ready and Ulrich Tepass

doi:10.1038/nature721

Abstract | Full Text | PDF (621K) | Supplementary information

See also: News and Views by Pichaud & Desplan

Letters to Nature

A velocity dipole in the distribution of radio galaxies p150

Chris Blake and Jasper Wall

doi:10.1038/416150a

First paragraph | Full Text | PDF (231K)

See also: News and Views by Ellis

Electrical discharge from a thundercloud top to the lower ionosphere p152

Victor P. Pasko, Mark A. Stanley, John D. Mathews, Umran S. Inan and Troy G. Wood

doi:10.1038/416152a

First paragraph | Full Text | PDF (287K) | Supplementary information

Formation of isomorphic Ir³⁺ and Ir⁴⁺ octamers and spin dimerization in the spinel CuIr₂S₄ p155

Paolo G. Radaelli, Y. Horibe, Matthias J. Gutmann, Hiroki Ishibashi, C. H. Chen, Richard M. Ibberson, Y. Koyama, Yew-San Hor, Valery Kiryukhin and Sang-Wook Cheong

doi:10.1038/416155a

First paragraph | Full Text | PDF (364K) | Supplementary information

Onset of Asian desertification by 22 Myr ago inferred from loess deposits in China p159

Z. T. Guo, William F. Ruddiman, Q. Z. Hao, H. B. Wu, Y. S. Qiao, R. X. Zhu, S. Z. Peng, J. J. Wei, B. Y. Yuan and T. S. Liu

doi:10.1038/416159a

First paragraph | Full Text | PDF (619K) | Supplementary information

Strong emission of methyl chloride from tropical plants p163

Yoko Yokouchi, Masumi Ikeda, Yoko Inuzuka and Tomohisa Yukawa

doi:10.1038/416163a

First paragraph | Full Text | PDF (177K)

A Jurassic mammal from South America p165

Oliver W. M. Rauhut, Thomas Martin, Edgardo Ortiz-Jaureguizar and Pablo Puerta

doi:10.1038/416165a

First paragraph | Full Text | PDF (260K) | Supplementary information

Bacterial growth and primary production along a north–south transect of the Atlantic Ocean p168

Hans-Georg Hoppe, Klaus Gocke, Regine Koppe and Christian Begler

doi:10.1038/416168a

First paragraph | Full Text | PDF (295K)

Hearing visual motion in depth p172

Norimichi Kitagawa and Shigeru Ichihara

doi:10.1038/416172a

First paragraph | Full Text | PDF (140K)

Embryonic assembly of a central pattern generator without sensory input p174

Maximiliano L. Suster and Michael Bate

doi:10.1038/416174a

First paragraph | Full Text | PDF (260K) | Supplementary information

See also: News and Views by Marder

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres p178

Shayan Izaddoost, Sang-Chul Nam, Manzoor A. Bhat, Hugo J. Bellen and Kwang-Wook Choi

doi:10.1038/nature720

First paragraph | Full Text | PDF (558K)

See also: News and Views by Pichaud & Desplan

Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors p183

Philippe Soubeyran, Katarzyna Kowanetz, Iwona Szymkiewicz, Wallace Y. Langdon and Ivan Dikic

doi:10.1038/416183a

First paragraph | Full Text | PDF (352K) | Supplementary information

See also: News and Views by Oved & Yarden

The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met p187

Annalisa Petrelli, Giorgio F. Gilestro, Stefania Lanzardo, Paolo M. Comoglio, Nicola Migone and Silvia Giordano

doi:10.1038/416187a

First paragraph | Full Text | PDF (245K) | Supplementary information

See also: News and Views by Oved & Yarden

Involvement of receptor-interacting protein 2 in innate and adaptive immune responses p190

Arnold I. Chin, Paul W. Dempsey, Kevin Bruhn, Jeff F. Miller, Yang Xu and Genhong Cheng

doi:10.1038/416190a

First paragraph | Full Text | PDF (201K)

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems p194

Koichi Kobayashi, Naohiro Inohara, Lorraine D. Hernandez, Jorge E. Galán, Gabriel Núñez, Charles A. Janeway, Ruslan Medzhitov and Richard A. Flavell

doi:10.1038/416194a

First paragraph | Full Text | PDF (358K) | Supplementary information

An amino-acid taste receptor p199

Greg Nelson, Jayaram Chandrashekar, Mark A. Hoon, Luxin Feng, Grace Zhao, Nicholas J. P. Ryba and Charles S. Zuker

doi:10.1038/nature726

First paragraph | Full Text | PDF (501K)

See also: News and Views by Anson

addendum: Virus-mediated killing of cells that lack p53 activity p202

Kenneth Raj, Phyllis Ogston and Peter Beard

doi:10.1038/416202a

Full Text | PDF (74K)

New on the Market

Spectroscopy and fluorometry p203

New ideas include kits — QC Paks — for validating microplate fluorometers.

doi:10.1038/416203a

Full Text | PDF (133K)

insight

Ultracold matter p205

Karen Southwell

doi:10.1038/416205a

Full Text | PDF (71K)

Cold atoms and quantum control p206

Steven Chu

doi:10.1038/416206a

Abstract | Full Text | PDF (220K)

Bose–Einstein condensation of atomic gases p211

James R. Anglin and Wolfgang Ketterle

doi:10.1038/416211a

Abstract | Full Text | PDF (1,644K)

Nonlinear and quantum atom optics p219

S. L. Rolston and W. D. Phillips

doi:10.1038/416219a

Abstract | Full Text | PDF (754K)

Quantum encounters of the cold kind p225

Keith Burnett, Paul S. Julienne, Paul D. Lett, Eite Tiesinga and Carl J. Williams

doi:10.1038/416225a

Abstract | Full Text | PDF (303K)

Optical frequency metrology p233

Th. Udem, R. Holzwarth and T. W. Hänsch

doi:10.1038/416233a

Abstract | Full Text | PDF (297K)

Quantum information processing with atoms and photons p238

C. Monroe

doi:10.1038/416238a

Abstract | Full Text | PDF (1,155K)