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Nature 415, 914-917 (6 February 2002) | doi:10.1038/nature716;
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- Bangalore, Karnataka 560099 India
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- Montreal, Quebec Canada
Hox protein mutation and macroevolution of the insect body plan
A fascinating question in biology is how molecular changes in developmental pathways lead to macroevolutionary changes in morphology. Mutations in homeotic (Hox) genes have long been suggested as potential causes of morphological evolution, and there is abundant evidence that some changes in Hox expression patterns correlate with transitions in animal axial pattern.
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