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Nature 415, 748-749 (14 February 2002) | doi:10.1038/415748a
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Professor of Microscopy (W2)
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Developmental biology: Precision patterning
Abstract
Many developmental events depend on gradients of key molecules to tell cells where they are. These gradients vary between embryos, but a noise-filtering mechanism ensures that development proceeds normally.
Embryos develop in a precise pattern that varies little from individual to individual within a given species. Such precision and reproducibility make this an excellent example of biological robustness.
- Nipam H. Patel and Sabbi Lall are in the Department of Organismal Biology and Anatomy, and the Howard Hughes Medical Institute, University of Chicago, 5841 South Maryland Avenue, MC1028, Chicago, Illinois 60637, USA.
e-mails: Email: npatel@midway.uchicago.edu and Email: slall@midway.uchicago.edu
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