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Nature 415, 484-485 (31 January 2002) | doi:10.1038/415484a

Cancer: The molecular outlook

Carlos Caldas1 & Samuel A. J. Aparicio1

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Many breast-cancer patients receive unnecessary treatment for possible tumour spread after the removal of a primary tumour. Molecular profiling should offer more accurate predictions of who needs such treatment.

The first step in rationally treating a disease is to assess the patient against a classification of diseases, the results being used to predict the person's response to various therapies. The effectiveness of the process depends on the quality of the classification.