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Nature 415, 129-131 (10 January 2002) | doi:10.1038/415129a

Molecular motors: Stretching the lever-arm theory

Michael A. Geeves

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Motor proteins are essential to life: without them, all cellular transport would grind to a halt. New results on the size of steps taken by one family of motors, the myosins, will fuel the debate about how they move.

Most organisms, whether they consist of a single cell or billions, can move in a directed way, an ability that is largely attributed to molecular motor proteins. Of these, myosin II is perhaps the best understood, because of its role in muscle contraction.