Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 415, 26-27 (3 January 2002) | doi:10.1038/415026a
nature jobs
Principal Scientist - In Vivo Pain Biologist
- GlaxoSmithKline
- Harlow, Essex United Kingdom
Postdoctoral Fellowship
- Lovelace Respiratory Research Institute
- Albuquerque, New Mexico
Ageing: The price of tumour suppression?
Gerardo Ferbeyre1 & Scott W. Lowe2
Top of page
Abstract
The p53 protein works to suppress cancer, so one might think that bumping up the levels of this protein would be a good idea. But this isn't so — mice with too much p53 age prematurely.
The p53 gene is often touted as 'the most frequently mutated gene in human cancer'. As a result, a great deal is known about it.
- Gerardo Ferbeyre is in the Department of Biochemistry, Université de Montréal, Montréal, Quebec, Canada, H3C 3J7.
e-mail: Email: g.ferbeyre@umontreal.ca - Scott W. Lowe is at the Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
e-mail: Email: lowe@cshl.edu
To read this story in full you will need to login or make a payment (see right).
