Table of contents
Volume 415 Number 6867 pp1-99
Opinion
Timely messages for the South p1
A WHO report delivers a powerful combination of analysis and economic judgement to suggest that developed countries have much to gain by significantly boosting their efforts to alleviate health problems in the developing world.
doi:10.1038/415001a
Towards more effective drug discovery p1
That's a key goal of a new Nature journal.
doi:10.1038/415001b
News
German task force outraged by changes to science fraud report p3
Quirin Schiermeier
doi:10.1038/415003a
Body identified as missing biologist p3
Erika Check
doi:10.1038/415003b
News
Online marine resource could soon be swimming with data p4
Jonathan Knight
doi:10.1038/415004a
Future funds in doubt as asteroid project wins short reprieve p4
Erika Check
doi:10.1038/415004b
Anthropologists split over misconduct claims p5
Rex Dalton
doi:10.1038/415005a
Museum staff strike to prevent loss of artefacts p5
doi:10.1038/415005b
news feature
Surviving a knockout blow p8
Disabling a gene in one mouse strain can be fatal — but in another strain it can produce animals that seem normal. Making sense of such results requires stamina and skill, says Helen Pearson.
Helen Pearson
doi:10.1038/415008a
The physics of the trading floor p10
Some physicists claim their modelling and data-analysis techniques can change the way we view stock markets. But mainstream economists have yet to be convinced, explains Mark Buchanan.
Mark Buchanan
doi:10.1038/415010a
Correspondence
Intuition and inspiration made Gamow a star turn p13
The astronomer's rare insight meant that his guesses were often surprisingly accurate.
Vera C. Rubin
doi:10.1038/415013a
Postdocs don't need reality to hit so hard p13
Maryse Bailly
doi:10.1038/415013b
Talking about regeneration p13
Jaume Baguñà
doi:10.1038/415013c
Fruitful synthesis of science and fiction p13
Preston J. MacDougall
doi:10.1038/415013d
Standardizing chemical risk assessment, at last p14
J. V. Tarazona
doi:10.1038/415014a
Commentary
1902 and all that p15
This year's offerings — calendars, kites and eruptions.
doi:10.1038/415015a
Book Reviews
The measure of a Victorian polymath p19
Pulling together the strands of Francis Galton's legacy to modern biology.
Garland E. Allen reviews Sir Francis Galton: From African Exploration to the Birth of Eugenics by Nicholas Wright Gillham
doi:10.1038/415019a
State-of-the-art oceanography p20
Detlef Quadfasel reviews Ocean Circulation & Climate: Observing and Modelling the Global Ocean
doi:10.1038/415020a
Monstrous manifestations p20
doi:10.1038/415020b
Down on the shore p21
doi:10.1038/415021a
Name that plant p21
P. F. Stevens reviews Guide to Standard Floras of the World by David G. Frodin
doi:10.1038/415021b
Science in culture p22
Josette Chen reviews
doi:10.1038/415022a
News and Views
Bose-Einstein condensation: Breaking up a superfluid p25
Ultracold atoms held in a three-dimensional pattern by a web of light beams can now be switched from a superfluid to an insulating state. This achievement may be useful for performing quantum computations.
Henk T. C. Stoof
doi:10.1038/415025a
Ageing: The price of tumour suppression? p26
The p53 protein works to suppress cancer, so one might think that bumping up the levels of this protein would be a good idea. But this isn't so — mice with too much p53 age prematurely.
Gerardo Ferbeyre and Scott W. Lowe
doi:10.1038/415026a
Cosmology: A baryometer is back p27
The usefulness of helium-3 as a probe of the early Universe has been in doubt. A rethink of stellar theory and new observational data put those doubts to rest.
Corinne Charbonnel
doi:10.1038/415027a
Neuroscience: Sounds, signals and space maps p29
The auditory system transforms information from one frame of reference into another to create a map of space in the brain. The source of a visual signal that guides this transformation in barn owls has now been found.
Catherine Carr
doi:10.1038/415029a
100 and 50 years ago p30
doi:10.1038/415030a
Astronomy: Magnetic bubbles in space p31
The origin of magnetic fields found in galaxies and galaxy clusters is unknown. Both models and observations suggest that extinct radio galaxies could be responsible.
Ellen G. Zweibel
doi:10.1038/415031a
Microbiology: Group effort in toxin synthesis p33
It is increasingly evident that bacterial cells cooperate for many purposes. New results show that the bacterium Enterococcus uses cell–cell signalling to coordinate toxin production.
Gary M. Dunny
doi:10.1038/415033a
Daedalus: Atmospheric charge p34
David Jones
doi:10.1038/415034a
Brief Communications
Human behaviour: Seeing through the face of deception p35
Thermal imaging offers a promising hands-off approach to mass security screening.
Ioannis Pavlidis, Norman L. Eberhardt and James A. Levine
doi:10.1038/415035a
First paragraph | Full Text | PDF (237K)
Satellite tagging: Expanded niche for white sharks p35
Andre M. Boustany, Scott F. Davis, Peter Pyle, Scot D. Anderson, Burney J. Le Boeuf and Barbara A. Block
doi:10.1038/415035b
First paragraph | Full Text | PDF (237K) | Supplementary information
Carnivorous plants: Mass march of termites into the deadly trap p36
Marlis A. Merbach, Dennis J. Merbach, Ulrich Maschwitz, Webber E. Booth, Brigitte Fiala and Georg Zizka
doi:10.1038/415036a
First paragraph | Full Text | PDF (190K)
Geoarchaeology (Communication arising): Did Nile flooding sink two ancient cities? p37
Rushdi Said
doi:10.1038/415037a
First paragraph | Full Text | PDF (85K)
Palaeobotany (Communications arising): Atmospheric CO2 from fossil plant cuticles p38
Hans Kerp
doi:10.1038/415038a
First paragraph | Full Text | PDF (43K)
Palaeobotany (Communications arising): Atmospheric CO2 from fossil plant cuticles p38
Gregory Retallack
doi:10.1038/415038b
Articles
Quantum phase transition from a superfluid to a Mott insulator in a gas of ultracold atoms p39
Markus Greiner, Olaf Mandel, Tilman Esslinger, Theodor W. Hänsch and Immanuel Bloch
doi:10.1038/415039a
Abstract | Full Text | PDF (351K)
See also: News and Views by Stoof
p53 mutant mice that display early ageing-associated phenotypes p45
Stuart D. Tyner, Sundaresan Venkatachalam, Jene Choi, Stephen Jones, Nader Ghebranious, Herbert Igelmann, Xiongbin Lu, Gabrielle Soron, Benjamin Cooper, Cory Brayton, Sang Hee Park, Timothy Thompson, Gerard Karsenty, Allan Bradley and Lawrence A. Donehower
doi:10.1038/415045a
Abstract | Full Text | PDF (538K)
See also: News and Views by Ferbeyre & Lowe
Letters to Nature
The cosmological density of baryons from observations of 3He+ in the Milky Way p54
T. M. Bania, Robert T. Rood and Dana S. Balser
doi:10.1038/415054a
First paragraph | Full Text | PDF (165K)
See also: News and Views by Charbonnel
Interstellar scintillation as the origin of the rapid radio variability of the quasar J1819+3845 p57
J. Dennett-Thorpe and A. G. de Bruyn
doi:10.1038/415057a
First paragraph | Full Text | PDF (454K)
Mesoscopic superconductor as a ballistic quantum switch p60
A. S. Mel'nikov and V. M. Vinokur
doi:10.1038/415060a
First paragraph | Full Text | PDF (164K)
A robust DNA mechanical device controlled by hybridization topology p62
Hao Yan, Xiaoping Zhang, Zhiyong Shen and Nadrian C. Seeman
doi:10.1038/415062a
First paragraph | Full Text | PDF (278K) | Supplementary information
Evolutionary speed limits inferred from the fossil record p65
James W. Kirchner
doi:10.1038/415065a
First paragraph | Full Text | PDF (381K) | Supplementary information
Resource-based niches provide a basis for plant species diversity and dominance in arctic tundra p68
Robert B. McKane, Loretta C. Johnson, Gaius R. Shaver, Knute J. Nadelhoffer, Edward B. Rastetter, Brian Fry, Anne E. Giblin, Knut Kielland, Bonnie L. Kwiatkowski, James A. Laundre and Georgia Murray
doi:10.1038/415068a
First paragraph | Full Text | PDF (145K)
Polyandrous females avoid costs of inbreeding p71
Tom Tregenza and Nina Wedell
doi:10.1038/415071a
First paragraph | Full Text | PDF (98K)
The optic tectum controls visually guided adaptive plasticity in the owl's auditory space map p73
Peter S. Hyde and Eric I. Knudsen
doi:10.1038/415073a
First paragraph | Full Text | PDF (468K) | Supplementary information
See also: News and Views by Carr
Stage-specific control of neuronal migration by somatostatin p77
Elina Yacubova and Hitoshi Komuro
doi:10.1038/415077a
First paragraph | Full Text | PDF (456K)
Inter-receptor communication through arrays of bacterial chemoreceptors p81
Jason E. Gestwicki and Laura L. Kiessling
doi:10.1038/415081a
First paragraph | Full Text | PDF (239K) | Supplementary information
Two-component regulator of Enterococcus faecalis cytolysin responds to quorum-sensing autoinduction p84
Wolfgang Haas, Brett D. Shepard and Michael S. Gilmore
doi:10.1038/415084a
First paragraph | Full Text | PDF (213K) | Supplementary information
See also: News and Views by Dunny
Identification of a host protein essential for assembly of immature HIV-1 capsids p88
Concepcion Zimmerman, Kevin C. Klein, Patti K. Kiser, Aalok R. Singh, Bonnie L. Firestein, Shannyn C. Riba and Jaisri R. Lingappa
doi:10.1038/415088a
First paragraph | Full Text | PDF (338K) | Supplementary information
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA p92
Marcella Calfon, Huiqing Zeng, Fumihiko Urano, Jeffery H. Till, Stevan R. Hubbard, Heather P. Harding, Scott G. Clark and David Ron
doi:10.1038/415092a
First paragraph | Full Text | PDF (299K) | Supplementary information
Superoxide activates mitochondrial uncoupling proteins p96
Karim S. Echtay, Damien Roussel, Julie St-Pierre, Mika B. Jekabsons, Susana Cadenas, Jeff A. Stuart, James A. Harper, Stephen J. Roebuck, Alastair Morrison, Susan Pickering, John C. Clapham and Martin D. Brand
doi:10.1038/415096a
First paragraph | Full Text | PDF (142K)
