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From the following article:

p53 mutant mice that display early ageing-associated phenotypes

Stuart D. Tyner, Sundaresan Venkatachalam, Jene Choi, Stephen Jones, Nader Ghebranious, Herbert Igelmann, Xiongbin Lu, Gabrielle Soron, Benjamin Cooper, Cory Brayton, Sang Hee Park, Timothy Thompson, Gerard Karsenty, Allan Bradley and Lawrence A. Donehower

Nature 415, 45-53(3 January 2002)

doi:10.1038/415045a

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Figure 1

Structure and expression of the mutant p53 m allele.

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Figure 2

Longevity in p53+/+, p53+/-, p53+/m, p53-/- and p53-/m mice.

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Figure 3

Transformation and p53 response phenotypes.

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Figure 4

Phenotypes of aged p53+/+ and p53+/m mice.

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Figure 5

Bone phenotypes in p53+/+ and p53+/m mice.

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Figure 6

Skin and hair growth phenotypes in p53+/+ and p53+/m mice.

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Figure 7

Stress responses in p53+/+ and p53+/m mice.

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Figure 8

Ageing-related phenotypes observed in pL53 transgenic mice.

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Table 1

Tumour types arising in p53+/-, p53+/+, p53+/m and pL53 mice

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Table 2

Ageing-related phenotypes in p53+/+, p53+/m and pL53 mice

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