Table of contents


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Naturejobs

Prospects

Backing a meeting of minds p3

Paul Smaglik

doi:10.1038/nj6866-03a


movers

Biology, Biology and Physics, Biotechnology, and Biotech Management p4

doi:10.1038/nj6866-04a


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Opinion

Time to halt the gravy train p829

As European integration gathers pace, the notion that scientists must be rewarded with tax-free salaries and other perks for working at a 'foreign' international laboratory has become an anachronism.

doi:10.1038/414829a


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News

Map data kept under wraps as Pentagon focuses on security p831

Jonathan Knight

doi:10.1038/414831a


Spain sets sights on fusion facility p831

Sally Goodman

doi:10.1038/414831b


Bush turns to Silicon Valley moguls for scientific advice p832

Tony Reichhardt

doi:10.1038/414832a


Canadian budget cranks up investment in research p832

David Spurgeon

doi:10.1038/414832b


EU ministers temper Framework reforms p833

Quirin Schiermeier

doi:10.1038/414833a


Planned merger worries Japan's nuclear researchers p833

David Cyranoski

doi:10.1038/414833b


British research audit may be last of its kind p834

David Adam

doi:10.1038/414834a


news in brief p835

doi:10.1038/414835a


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2001 IN CONTEXT

The big picture: Science in a changed world p836

It should have been a year of celebration, as science passed a major milestone with the publication of the human genome sequence. Instead, a global economic slowdown and the world-changing events of 11 September have cast a long shadow. Nature's reporters look back on a tumultuous year.

Colin Macilwain

doi:10.1038/414836a


Bioweapons: Delivering death in the mail p837

Jonathan Knight

doi:10.1038/414837a


Regenerative medicine: A world of difference p838

Peter Aldhous

doi:10.1038/414838a


US science policy: Under new management p839

Colin Macilwain

doi:10.1038/414839a


Animal health: The killing fields p839

Jim Giles

doi:10.1038/414839b


Postgenomics: Data, data, everywhere... p840

Declan Butler

doi:10.1038/414840a


Big science: Down to Earth with a bump p841

David Adam and Tony Reichhardt

doi:10.1038/414841a


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Correspondence

Beware the baited hook of publicity p843

Headlines are tempting but lead to disillusionment — and a sour taste with your spaghetti.

Michele Pagano

doi:10.1038/414843a


Industry and evaluation p843

Les Firbank

doi:10.1038/414843b


Dogs won more fame than female colleagues p843

Caroline L. Herzenberg

doi:10.1038/414843c


Top

Book Reviews

The poetic mystery of dark matter p845

The life and poetry of astronomer Rebecca Elson.

Ingrid Fiske reviews A Responsibility to Awe by Rebecca Elson

doi:10.1038/414845a


A nebulous secret revealed p845

doi:10.1038/414845b


The sorry story of drug prohibition p846

Leslie Iversen reviews The Pursuit of Oblivion: A Global History of Narcotics 1500–2000 by Richard Davenport-Hines

doi:10.1038/414846a


Going organic p847

doi:10.1038/414847a


From clay to computer screen p847

Maurice Pope reviews A History of Writing by Steven Roger Fischer

doi:10.1038/414847b


Golem schmolem p848

Henry Gee reviews Kiln People by David Brin

doi:10.1038/414848a


On the jungle beat p848

doi:10.1038/414848b


A celebration of science p849

Fran Balkwill reviews The Science Book edited by Peter Tallack

doi:10.1038/414849a


A clever idea to swallow p850

Michael Gillmer reviews This Man's Pill: Reflections on the 50th Birthday of the Pill by Carl Djerassi and Sexual Chemistry: A History of the Contraceptive Pill by Lara V. Marks

doi:10.1038/414850a


Top

words

Sines in terse verse p851

Coding large numbers in synthetic words made them easier to memorize.

Roddam Narasimha

doi:10.1038/414851a


Top

News and Views

Astronomy: Blinded by the light p853

If gamma-ray bursts released their energy uniformly in all directions they would be the most powerful events in the Universe. Astronomers are trying to see past the glare to determine the true energy.

Stan Woosley

doi:10.1038/414853a


The human genome: Part three in the book of genes p854

Working out the draft sequence of the human genome was a landmark achievement. But there's lots more to be done before the finished product is available. The complete sequence of chromosome 20 sets us on the way.

Masahira Hattori and Todd D. Taylor

doi:10.1038/414854a


Biomechanics: Damper for bad vibrations p855

Some muscle fibres in the legs of horses seem to be evolutionary leftovers with no function. But in fact they may act to damp damaging vibrations generated in the leg as the horse runs.

R. McNeill Alexander

doi:10.1038/414855a


Meteoritics: Life's sweet beginnings? p857

Sugars are common components of organisms on Earth. So their discovery in a meteorite from a lifeless part of the asteroid belt has implications for theories of the origin of life.

Mark A. Sephton

doi:10.1038/414857a


Molecular biology: Specifying transcription p858

To switch on the right genes at the right times, our cells rely on many different proteins. Some help to remodel the architecture of the genome, and are remarkably choosy about which other proteins they work with.

Ian F. G. King and Robert E. Kingston

doi:10.1038/414858a


100 and 50 years ago p859

doi:10.1038/414859a


Geophysics: Deep down at Chicxulub p861

The best-preserved large impact crater on Earth is overlain by a kilometre of sediment. It is possible to look not only through that wrapping but also beyond, at the effects of the impact at the crust–mantle boundary.

Jay Melosh

doi:10.1038/414861a


Daedalus: Away with oxygen! p862

David Jones

doi:10.1038/414862a


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Brief Communications

Health: Endothelin-1 synthesis reduced by red wine p863

Red wines confer extra benefit when it comes to preventing coronary heart disease.

Roger Corder, Julie A. Douthwaite, Delphine M. Lees, Noorafza Q. Khan, Ana Carolina Viseu dos Santos, Elizabeth G. Wood and Martin J. Carrier

doi:10.1038/414863a


Image processing: Fractals in pixellated video feedback p864

Johannes Courtial, Jonathan Leach and Miles J. Padgett

doi:10.1038/414864a


Top

Articles

The DNA sequence and comparative analysis of human chromosome 20 p865

and The Wellcome Trust Sanger Institute

doi:10.1038/414865a

See also: News and Views by Hattori & Taylor


Structural basis of water-specific transport through the AQP1 water channel p872

Haixin Sui, Bong-Gyoon Han, John K. Lee, Peter Walian and Bing K. Jap

doi:10.1038/414872a


Top

Letters to Nature

Carbonaceous meteorites as a source of sugar-related organic compounds for the early Earth p879

George Cooper, Novelle Kimmich, Warren Belisle, Josh Sarinana, Katrina Brabham and Laurence Garrel

doi:10.1038/414879a

See also: News and Views by Sephton


Experimental realization of Shor's quantum factoring algorithm using nuclear magnetic resonance p883

Lieven M. K. Vandersypen, Matthias Steffen, Gregory Breyta, Costantino S. Yannoni, Mark H. Sherwood and Isaac L. Chuang

doi:10.1038/414883a


A limit on spin–charge separation in high-Tc superconductors from the absence of a vortex-memory effect p887

D. A. Bonn, Janice C. Wynn, Brian W. Gardner, Yu-Ju Lin, Ruixing Liang, W. N. Hardy, J. R. Kirtley and K. A. Moler

doi:10.1038/414887a


Folding-driven synthesis of oligomers p889

Keunchan Oh, Kyu-Sung Jeong and Jeffrey S. Moore

doi:10.1038/414889a


Striped iron zoning of olivine induced by dislocation creep in deformed peridotites p893

J. Ando, Y. Shibata, Y. Okajima, K. Kanagawa, M. Furusho and N. Tomioka

doi:10.1038/414893a


Horses damp the spring in their step p895

Alan M. Wilson, M. Polly McGuigan, Anne Su and Anton J. van den Bogert

doi:10.1038/414895a

See also: News and Views by Hattori & Taylor


Maternal control of resting-egg production in Daphnia p899

Victor Alekseev and Winfried Lampert

doi:10.1038/414899a


The genetic architecture of divergence between threespine stickleback species p901

Catherine L. Peichel, Kirsten S. Nereng, Kenneth A. Ohgi, Bonnie L. E. Cole, Pamela F. Colosimo, C. Alex Buerkle, Dolph Schluter and David M. Kingsley

doi:10.1038/414901a


Dynamic properties of neurons in cortical area MT in alert and anaesthetized macaque monkeys p905

Christopher C. Pack, Vladimir K. Berezovskii and Richard T. Born

doi:10.1038/414905a


Noggin and retinoic acid transform the identity of avian facial prominences p909

S.-H. Lee, K. K. Fu, J. N. Hui and J. M. Richman

doi:10.1038/414909a


Gene defect in ectodermal dysplasia implicates a death domain adapter in development p913

Denis J. Headon, Stephanie A. Emmal, Betsy M. Ferguson, Abigail S. Tucker, Monica J. Justice, Paul T. Sharpe, Jonathan Zonana and Paul A. Overbeek

doi:10.1038/414913a


Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage p916

Akio Ohta and Michail Sitkovsky

doi:10.1038/414916a


MIF regulates innate immune responses through modulation of Toll-like receptor 4 p920

Thierry Roger, John David, Michel P. Glauser and Thierry Calandra

doi:10.1038/414920a


Selectivity of chromatin-remodelling cofactors for ligand-activated transcription p924

Bryan Lemon, Carla Inouye, David S. King and Robert Tjian

doi:10.1038/414924a

See also: News and Views by King & Kingston


Stimulatory effect of splicing factors on transcriptional elongation p929

Yick W. Fong and Qiang Zhou

doi:10.1038/414929a


Crystal structure of an Eph receptor–ephrin complex p933

Juha-Pekka Himanen, Kanagalaghatta R. Rajashankar, Martin Lackmann, Chad A. Cowan, Mark Henkemeyer and Dimitar B. Nikolov

doi:10.1038/414933a


correction: Neurogenesis in the adult is involved in the formation of trace memories p938

Tracey J. Shors, George Miesegaes, Anna Beylin, Mingrui Zhao, Tracy Rydel and Elizabeth Gould

doi:10.1038/414938a


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