Table of contents


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Naturejobs

Prospects

Take control of your destiny p3

Paul Smaglik

doi:10.1038/nj6865-03a


regions

Changing fortunes Australia p4

Peter Pockley

doi:10.1038/nj6865-04a


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Opinion

Educating future scientists p673

Instead of helplessly pondering a new trove of data for guidance on how to improve science education, researchers should better exploit existing mechanisms for helping out at their local schools.

doi:10.1038/414673a


Europe must unite to preserve its heritage p673

The European Commission should not lose its enthusiasm for supporting research into the preservation of cultural heritage.

doi:10.1038/414673b


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News

Bioweapons treaty in disarray as US blocks plans for verification p675

Declan Butler

doi:10.1038/414675a


Nobel officials recoil from expenses offer p676

David Cyranoski

doi:10.1038/414676a


Mathematicians poised for major funding boost p676

Erica Klarreich

doi:10.1038/414676b


Trial halted after gene shows up in semen p677

Nell Boyce

doi:10.1038/414677a


Need for vaccine stocks questioned p677

Erika Check

doi:10.1038/414677b


Wellcome bid sees Crick archive return home p678

Alison Abbott and Rex Dalton

doi:10.1038/414678a


Jodrell Bank survives shake-up of UK astronomy p678

David Adam

doi:10.1038/414678b


Partners' anger mounts over NASA plans for space station p679

Tony Reichhardt

doi:10.1038/414679a


Europe's Mars mission to pay out for Beagle lander p679

Sally Goodman

doi:10.1038/414679b


news in brief p680

doi:10.1038/414680a


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news feature

Which way to energy utopia? p682

The vehicles of the future will almost certainly be powered by hydrogen. But no one is sure exactly how to get drivers to kick their fossil-fuel habit. Mark Schrope weighs up the options.

Mark Schrope

doi:10.1038/414682a


The curtain falls p685

Theatre seemed the ideal way for US bioprospectors working in Mexico to tell local people about their work. But did the plays distract attention from the involvement of commercial interests? Rex Dalton reports.

Rex Dalton

doi:10.1038/414685a


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Correspondence

Crops grown on set-aside land bring wild birds back to the fields p687

Monitoring is under way, and results so far are promising.

Chris Stoate and Dave Parish

doi:10.1038/414687a


Schemes are monitored and effective in the UK p687

Peter D. Carey

doi:10.1038/414687b


War: no time for dissent p687

Arno Arrak

doi:10.1038/414687c


Church backing depends on ethical use of animals p687

Archbishop Monsignor Elio Sgreccia, Don Maurizio Calipari and Marialuisa Lavitrano

doi:10.1038/414687d


Top

Book Reviews

Out of thin air p689

Towards an understanding of our responses to high altitude.

Sue Jackson reviews High Altitude: An Exploration of Human Adaptation

doi:10.1038/414689a


Lifting the curtain on the Nobels p690

Aant Elzinga reviews The Politics of Excellence: Behind the Nobel Prize in Science by Robert Marc Friedman

doi:10.1038/414690a


Sex appeal of a musical insect p691

Marlene Zuk reviews Katydids and Bush-Crickets: Reproductive Behavior and Evolution of the Tettigoniidae by Darryl T. Gwynne

doi:10.1038/414691a


A turn-up for worms p691

doi:10.1038/414691b


Science in culture p692

Martin Kemp reviews

doi:10.1038/414692a


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concepts

mRNA readout at 40 p693

John F. Atkins and Raymond F. Gesteland

doi:10.1038/414693a


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News and Views

Waving goodbye to measles p695

An innovative way of analysing statistics on measles incidence in England and Wales since 1944 reveals recurring waves of infection originating in large cities. The information can guide strategies for preventing the disease.

Peter M. Strebel and Stephen L. Cochi

doi:10.1038/414695a


High-temperature superconductivity: Charged with smuggling heat p696

Good conductors of heat are usually good at conducting electricity. So the discovery that electrons in a superconductor can carry an unauthorized amount of heat at low temperatures raises many questions.

Kamran Behnia

doi:10.1038/414696a


100 and 50 years ago p697

doi:10.1038/414697a


Biomaterials: Sacrificial bonds heal bone p699

The toughness of bone is usually attributed to its collagen, but how does it work? New evidence shows that molecular bonds can temporarily sacrifice themselves to absorb impacts.

John Currey

doi:10.1038/414699a


Space physics: Rhythms of the auroral dance p700

Earlier this year, the four satellites of the Cluster mission passed through part of the electric circuit that causes aurorae. Their observations support the view that intense aurorae form in regions largely devoid of electrons.

Patrick T. Newell

doi:10.1038/414700a


Immunology: Bug detectors p701

Insects and mammals are thought to have similar 'innate' immune responses to infectious microorganisms. But there are differences, and even more now emerge from studies of how insects detect bacteria.

Tsuneyasu Kaisho and Shizuo Akira

doi:10.1038/414701a


Chemistry: An end to the protection racket p703

To modify a specific site on a molecule that has several similar sites, organic chemists have had to use cumbersome 'protecting groups'. New peptide catalysts with remarkable selectivities offer a protection-free alternative.

David Gani

doi:10.1038/414703a


Medicine: Short cut to disease genes p705

There are thousands of inherited human diseases. For the most part, the genes that are mutated in these diseases are unknown. But a new approach could save time and effort in identifying the genes responsible.

Alan F. Wright and Veronica Van Heyningen

doi:10.1038/414705a


Daedalus: Reduced bandwidth p706

David Jones

doi:10.1038/414706a


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Brief Communications

Laterality in tool manufacture by crows p707

Neural processing and not ecological factors may influence 'handedness' in these birds.

Gavin R. Hunt, Michael C. Corballis and Russell D. Gray

doi:10.1038/414707a


Light emission: A temperature-tunable random laser p708

Diederik S. Wiersma and Stefano Cavalieri

doi:10.1038/414708a


Seed development (Communication arising): Early paternal gene activity in Arabidopsis p709

Dolf Weijers, Niko Geldner, Remko Offringa and Gerd Jürgens

doi:10.1038/414709a


Seed development (Communication arising): Early paternal gene activity in Arabidopsis p710

Jean-Philippe Vielle-Calzada, Ramamurthy Baskar and Ueli Grossniklaus

doi:10.1038/414710a


correction: Night-time predation by Steller sea lions p710

doi:10.1038/414710b


correction: Transatlantic robot-assisted telesurgery p710

doi:10.1038/414710c


correction: Peptide antibiotics in mast cells of fish p710

doi:10.1038/414710d


erratum: Nitrate flux in the Mississippi River p710

doi:10.1038/414710e


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Articles

Breakdown of Fermi-liquid theory in a copper-oxide superconductor p711

R. W. Hill, Cyril Proust, Louis Taillefer, P. Fournier and R. L. Greene

doi:10.1038/414711a

See also: News and Views by Behnia


Travelling waves and spatial hierarchies in measles epidemics p716

B. T. Grenfell, O. N. Bjørnstad and J. Kappey

doi:10.1038/414716a

See also: News and Views by Strebel & Cochi


Top

Letters to Nature

Temporal evolution of the electric field accelerating electrons away from the auroral ionosphere p724

G. T. Marklund, N. Ivchenko, T. Karlsson, A. Fazakerley, M. Dunlop, P.-A. Lindqvist, S. Buchert, C. Owen, M. Taylor, A. Vaivalds, P. Carter, M. André and A. Balogh

doi:10.1038/414724a

See also: News and Views by T. Newell


A one-dimensional chain state of vortex matter p728

Alexander Grigorenko, Simon Bending, Tsuyoshi Tamegai, Shuuichi Ooi and Mohamed Henini

doi:10.1038/414728a


High-temperature ultrafast polariton parametric amplification in semiconductor microcavities p731

M. Saba, C. Ciuti, J. Bloch, V. Thierry-Mieg, R. André, Le Si Dang, S. Kundermann, A. Mura, G. Bongiovanni, J. L. Staehli and B. Deveaud

doi:10.1038/414731a


Hierarchical self-assembly of metal nanostructures on diblock copolymer scaffolds p735

Ward A. Lopes and Heinrich M. Jaeger

doi:10.1038/414735a


Himalayan tectonics explained by extrusion of a low-viscosity crustal channel coupled to focused surface denudation p738

C. Beaumont, R. A. Jamieson, M. H. Nguyen and B. Lee

doi:10.1038/414738a


Effect of acoustic clutter on prey detection by bats p742

Raphaël Arlettaz, Gareth Jones and Paul A. Racey

doi:10.1038/414742a


Evidence for the evolution of multiple genomes in arbuscular mycorrhizal fungi p745

Gerrit Kuhn, Mohamed Hijri and Ian R. Sanders

doi:10.1038/414745a


Transmission potential of smallpox in contemporary populations p748

Raymond Gani and Steve Leach

doi:10.1038/414748a


Imperfect vaccines and the evolution of pathogen virulence p751

Sylvain Gandon, Margaret J. Mackinnon, Sean Nee and Andrew F. Read

doi:10.1038/414751a


Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein p756

Tatiana Michel, Jean-Marc Reichhart, Jules A. Hoffmann and Julien Royet

doi:10.1038/414756a

See also: News and Views by Kaisho & Akira


A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei p759

Miguel Navarro and Keith Gull

doi:10.1038/414759a


Thymus medulla consisting of epithelial islets each derived from a single progenitor p763

Hans-Reimer Rodewald, Sabine Paul, Corinne Haller, Horst Bluethmann and Carmen Blum

doi:10.1038/414763a


c-Myc regulates mammalian body size by controlling cell number but not cell size p768

Andreas Trumpp, Yosef Refaeli, Thordur Oskarsson, Stephan Gasser, Mark Murphy, Gail R. Martin and J. Michael Bishop

doi:10.1038/414768a


Bone indentation recovery time correlates with bond reforming time p773

James B. Thompson, Johannes H. Kindt, Barney Drake, Helen G. Hansma, Daniel E. Morse and Paul K. Hansma

doi:10.1038/414773a

See also: News and Views by Currey


Bacteriophytochromes are photochromic histidine kinases using a biliverdin chromophore p776

Seong-Hee Bhoo, Seth J. Davis, Joseph Walker, Baruch Karniol and Richard D. Vierstra

doi:10.1038/414776a


erratum: The rhythm of microbial adaptation p779

Philip Gerrish

doi:10.1038/414779a


Top

insight

foreword

Diabetes p781

doi:10.1038/414781a


review article

Global and societal implications of the diabetes epidemic p782

Paul Zimmet, K. G. M. M. Alberti and Jonathan Shaw

doi:10.1038/414782a


Diabetes mellitus and genetically programmed defects in beta-cell function p788

Graeme I. Bell and Kenneth S. Polonsky

doi:10.1038/414788a


beta-Cell death during progression to diabetes p792

Diane Mathis, Luis Vence and Christophe Benoist

doi:10.1038/414792a


Insulin signalling and the regulation of glucose and lipid metabolism p799

Alan R. Saltiel and C. Ronald Kahn

doi:10.1038/414799a


Mitochondrial function in normal and diabetic beta-cells p807

Pierre Maechler and Claes B. Wollheim

doi:10.1038/414807a


Biochemistry and molecular cell biology of diabetic complications p813

Michael Brownlee

doi:10.1038/414813a


New drug targets for type 2 diabetes and the metabolic syndrome p821

David E. Moller

doi:10.1038/414821a


corporate support

BRISTOL-MYERS SQUIBB AND DIABETES: Basic Science, Clinical Development, Global Surveillance p828

Peter S. Ringrose, Ph. D.

doi:10.1038/414828a


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