Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 414, 701-703 (13 December 2001) | doi:10.1038/414701a
Open Innovation Challenges
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
nature jobs
Senior Medical Writer
- Cactus Global
- Mumbai 400053 India
Postdoc in Computational Cancer Genomics
- Max Planck Institute for Neurological Research, Cologne, Germany
- Cologne, Germany
Immunology: Bug detectors
Tsuneyasu Kaisho1 & Shizuo Akira1
Abstract
Insects and mammals are thought to have similar 'innate' immune responses to infectious microorganisms. But there are differences, and even more now emerge from studies of how insects detect bacteria.
To respond rapidly to invading microorganisms, animals call on their innate immune systems. These consist of microbe-detecting molecules, which are connected to cascades of signalling proteins that in turn activate immune cells.
- Tsuneyasu Kaisho and Shizuo Akira are in the Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, and SORST, Japan Science and Technology Corporation, Japan.
Correspondence to: Shizuo Akira1 e-mail: Email: sakira@biken.osaka-u.ac.jp
To read this story in full you will need to login or make a payment (see right).

