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Nature 414, 29-31 (1 November 2001) | doi:10.1038/35102139
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Cell biology: Bacteria thread the needle
Craig L. Smith1 & Scott J. Hultgren1
Abstract
When bacteria attack another organism, one of the first steps is the injection of 'virulence effector proteins' into its cells. Two of the main players in such a system have been caught in action.
Many bacterial pathogens use a complex secretion system to inject proteins, known as 'effectors', into target host cells. This process is part of a molecular subversion tactic that allows bacteria to persist and cause disease, and requires specific molecular chaperones.
- Craig L. Smith and Scott J. Hultgren are in the Department of Molecular Microbiology, Washington University School of Medicine, Box 8230, 660 South Euclid Avenue, St Louis, Missouri 63110, USA.
e-mail: Email: smith@borcim.wustl.edu
Email: hultgren@borcim.wustl.edu
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