Table of contents
Volume 413 Number 6858 pp3-878
Naturejobs
prospectsGetting a handle on data p3
Paul Smaglik
doi:10.1038/35101774
CAREERS AND RECRUITMENT
A permanent education p4
As data analysis shifts towards protein expression and structure determination, demands for standardization and ease of access are leaving bioinformaticians scrambling to keep their skills up to date, says Helen Gavaghan.
Helen Gavaghan
doi:10.1038/35101776
Training in a hybrid discipline p6
Courses to teach bioinformatics are starting to spring up all over North America. But the interdisciplinary nature of the subject means that there is a severe lack of experienced instructors, so the quality may vary between programmes, warns Potter Wickware.
Potter Wickware
doi:10.1038/35101783
Playing catch-up p8
Japan's government is belatedly realizing that it needs to increase funding for training in bioinformatics, says Robert Triendl. But lack of specialists in the field could hinder the country's efforts.
Robert Triendl
doi:10.1038/35101788
Opinion
Europe needs to pull its weight in research p757
A broader vision of a pan-European research enterprise will remain just that until the continent's nation states become more imaginative in their approaches to collaboration.
doi:10.1038/35101720
A Goldin legacy p757
The US space programme will miss the colour, character and energy that NASA's departing administrator brought to his job.
doi:10.1038/35101722
News
Storm clouds gather over science as war build-up accelerates p759
Matthew Davis
doi:10.1038/35101724
Fallout from terrorism hits summits on developing world p759
K. S. Jayaraman and Philipp Weis
doi:10.1038/35101727
Brain mix-up leaves BSE research in turmoil p760
Declan Butler
doi:10.1038/35101729
Grants to help women climb academic ladder p761
Rex Dalton
doi:10.1038/35101732
Proposed scheme will scrutinize student supervisors p761
David Adam
doi:10.1038/35101735
NASA head bows out after a record run p762
William Triplett
doi:10.1038/35101738
Faculty concerns cost university venture-capital funds p762
Rex Dalton
doi:10.1038/35101741
Workshop prepares ground for human proteome project p763
Alison Abbott
doi:10.1038/35101743
Confusion over law leaves stem-cell research in the lurch p763
Xavier Bosch
doi:10.1038/35101746
news feature
Cryptography on the front line p766
As the 'war on terrorism' unfolds, some politicians are calling for controls on the availability of encryption software. But many computer scientists claim such moves would play into the terrorists' hands. David Adam reports.
David Adam
doi:10.1038/35101752
Science sans frontières p768
Will the European Union's member states ever put the goal of continental cohesion in science ahead of their individual national interests? Quirin Schiermeier considers the prospects for creating a 'European Research Area'.
Quirin Schiermeier
doi:10.1038/35101757
Correspondence
Masai Mara tourism reveals partnership benefits p771
Wise use of income could satisfy local communities while aiding conservation efforts.
M. J. Walpole and N. Leader-Williams
doi:10.1038/35101762
Italian immunology well but hoping to do better p771
Gianni Marone
doi:10.1038/35101764
Postdocs in France need less red tape, more cash p771
Andrew A. Munk
doi:10.1038/35101766
Planned law could put German research at risk p772
Thomas Jentsch
Hunger added an edge to Vincent's sharp wit p772
Ajoy K. Baksi
doi:10.1038/35101770
Bacteria in biofilms are living an unnatural life p772
David L. Kirchman
doi:10.1038/35101772
Commentary
Protecting privacy and liberty p773
The events of 11 September offer a rare chance to rethink public security.
doi:10.1038/35101663
Book Reviews
Honest Jim: the sequel p775
Further misadventures of one of the most influential scientists of our day.
Horace Freeland Judson reviews Genes, Girls and Gamow by James D. Watson
doi:10.1038/35101634
Clock-watching at sea p776
doi:10.1038/35101637
The world within the skull p776
Ilya Farber reviews I of the Vortex: From Neurons to Self by Rodolfo Llinás
doi:10.1038/35101640
So why is it colder in winter? p777
Peter Coles reviews Heavenly Errors: Misconceptions about the Real Nature of the Universe by Neil F. Comins
doi:10.1038/35101644
erratum p778
doi:10.1038/35101646
Science in culture p778
Martin Kemp reviews
doi:10.1038/35101648
words
Wondrous order p779
Could the prosaic vernacular of science benefit from a little enthusiasm for nature's beauty?
Matthew Cobb
doi:10.1038/35101666
News and Views
Preserved for the afterlife p783
Ancient Egyptians used sophisticated combinations of natural substances to embalm the human body. Over time, they modified their recipes to balance quality of preservation with cost and availability of materials.
Sarah Wisseman
doi:10.1038/35101673
Molecular dynamics: Slick switching of X-rays p784
The structures of crystals, from metals to proteins, have successfully been explored with X-rays. An ultrafast switch turns this idea around and uses a crystal to control the timing of X-ray pulses.
Ferenc Krausz and Christian Spielmann
doi:10.1038/35101677
100 and 50 years ago p785
doi:10.1038/35101680
Developmental biology: Solving a sticky problem p787
The Wnt family of proteins is a large one. Various combinations of its members control all sorts of developmental processes, including, it now seems, a pathway involving cell adhesion.
Christof Niehrs
doi:10.1038/35101682
Condensed-matter physics: Magnetic spins that last for ever p788
Phase transitions occurring at a temperature of absolute zero — quantum phase transitions — are hard to measure. A new type of quantum phase transition is now predicted to occur in two dimensions, rather than three.
Piers Coleman
doi:10.1038/35101685
Archaeology: Those elusive Neanderthals p791
The 'how, where and when' of possible Neanderthal coexistence with Cro-Magnons, and their extinction, continue to exercise a varied community of researchers. The latest interpretations of the fossil and archaeological records were aired at two meetings.
Chris Stringer and William Davies
doi:10.1038/35101688
Daedalus: The meaning of junk p792
David Jones
doi:10.1038/35101691
Brief Communications
Motor-cortical activity in tetraplegics p793
It may eventually be feasible to reconstruct voluntary motor activity in the paralysed.
Shy Shoham, Eric Halgren, Edwin M. Maynard and Richard A. Normann
doi:10.1038/35101651
First paragraph | Full Text | PDF (119K)
Ornithology: Arctic waders are not capital breeders p794
Marcel Klaassen, Åke Lindström, Hans Meltofte and Theunis Piersma
doi:10.1038/35101654
First paragraph | Full Text | PDF (131K)
Intracellular signalling: Key enzyme in leptin-induced anorexia p794
Kevin D. Niswender, Gregory J. Morton, Walter H. Stearns, Christopher J. Rhodes, Martin G. Myers, Jr and Michael W. Schwartz
doi:10.1038/35101657
First paragraph | Full Text | PDF (131K)
Tumour biology (Communication arising): Weakening link to colorectal cancer? p796
M. Barbier, S. Attoub, R. Calvez, M. Laffargue, A. Jarry, M. Mareel, F. Altruda, C. Gespach, D. Wu, B. Lu, E. Hirsch and M. P. Wymann
doi:10.1038/35101660
First paragraph | Full Text | PDF (94K)
Review
Morphogen gradient interpretation p797
J. B. Gurdon and P.-Y. Bourillot
doi:10.1038/35101500
Abstract | Full Text | PDF (234K)
Articles
Locally critical quantum phase transitions in strongly correlated metals p804
Qimiao Si, Silvio Rabello, Kevin Ingersent and J. Lleweilun Smith
doi:10.1038/35101507
Abstract | Full Text | PDF (171K)
See also: News and Views by Coleman
Ion conduction pore is conserved among potassium channels p809
Zhe Lu, Angela M. Klem and Yajamana Ramu
doi:10.1038/35101535
Abstract | Full Text | PDF (235K)
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria p814
Frank Schlünzen, Raz Zarivach, Jörg Harms, Anat Bashan, Ante Tocilj, Renate Albrecht, Ada Yonath and François Franceschi
doi:10.1038/35101544
Abstract | Full Text | PDF (602K)
Letters to Nature
Energy spectra of quantum rings p822
A. Fuhrer, S. Lüscher, T. Ihn, T. Heinzel, K. Ensslin, W. Wegscheider and M. Bichler
doi:10.1038/35101552
First paragraph | Full Text | PDF (304K)
Coherent control of pulsed X-ray beams p825
M. F. DeCamp, D. A. Reis, P. H. Bucksbaum, B. Adams, J. M. Caraher, R. Clarke, C. W. S. Conover, E. M. Dufresne, R. Merlin, V. Stoica and J. K. Wahlstrand
doi:10.1038/35101560
First paragraph | Full Text | PDF (214K)
See also: News and Views by Krausz & Spielmann
Spin-dependent exciton formation in 
-conjugated compounds p828
J. S. Wilson, A. S. Dhoot, A. J. A. B. Seeley, M. S. Khan, A. Köhler and R. H. Friend
doi:10.1038/35101565
First paragraph | Full Text | PDF (280K)
Superconductivity in single crystals of the fullerene C70 p831
J. H. Schön, Ch. Kloc, T. Siegrist, M. Steigerwald, C. Svensson and B. Batlogg
doi:10.1038/35101577
First paragraph | Full Text | PDF (374K)
Magma storage beneath Axial volcano on the Juan de Fuca mid-ocean ridge p833
M. West, W. Menke, M. Tolstoy, S. Webb and R. Sohn
doi:10.1038/35101581
First paragraph | Full Text | PDF (790K)
Organic chemistry of embalming agents in Pharaonic and Graeco-Roman mummies p837
Stephen A. Buckley and Richard P. Evershed
doi:10.1038/35101588
First paragraph | Full Text | PDF (251K)
See also: News and Views by Wisseman
Local interactions predict large-scale pattern in empirically derived cellular automata p841
J. Timothy Wootton
doi:10.1038/35101595
First paragraph | Full Text | PDF (271K)
Perceptual learning without perception p844
Takeo Watanabe, José E. Náñez and Yuka Sasaki
doi:10.1038/35101601
First paragraph | Full Text | PDF (219K)
Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18 p848
J. Parkhill, G. Dougan, K. D. James, N. R. Thomson, D. Pickard, J. Wain, C. Churcher, K. L. Mungall, S. D. Bentley, M. T. G. Holden, M. Sebaihia, S. Baker, D. Basham, K. Brooks, T. Chillingworth, P. Connerton, A. Cronin, P. Davis, R. M. Davies, L. Dowd, N. White, J. Farrar, T. Feltwell, N. Hamlin, A. Haque, T. T. Hien, S. Holroyd, K. Jagels, A. Krogh, T. S. Larsen, S. Leather, S. Moule, P. Ó'Gaora, C. Parry, M. Quail, K. Rutherford, M. Simmonds, J. Skelton, K. Stevens, S. Whitehead and B. G. Barrell
doi:10.1038/35101607
First paragraph | Full Text | PDF (1,027K) | Supplementary information
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2 p852
Michael McClelland, Kenneth E. Sanderson, John Spieth, Sandra W. Clifton, Phil Latreille, Laura Courtney, Steffen Porwollik, Johar Ali, Mike Dante, Feiyu Du, Shunfang Hou, Dan Layman, Shawn Leonard, Christine Nguyen, Kelsi Scott, Andrea Holmes, Neenu Grewal, Elizabeth Mulvaney, Ellen Ryan, Hui Sun, Liliana Florea, Webb Miller, Tamberlyn Stoneking, Michael Nhan, Robert Waterston and Richard K. Wilson
doi:10.1038/35101614
First paragraph | Full Text | PDF (317K) | Supplementary information
Frizzled-7 signalling controls tissue separation during Xenopus gastrulation p856
Rudolf Winklbauer, Araceli Medina, Rajeeb K. Swain and Herbert Steinbeisser
doi:10.1038/35101621
First paragraph | Full Text | PDF (320K)
See also: News and Views by Niehrs
Gene expression in Pseudomonas aeruginosa biofilms p860
Marvin Whiteley, M. Gita Bangera, Roger E. Bumgarner, Matthew R. Parsek, Gail M. Teitzel, Stephen Lory and E. P. Greenberg
doi:10.1038/35101627
First paragraph | Full Text | PDF (436K)
New on the Market
Oligonucleotides on view p865
Buying, hybridizing, and measuring oligonucleotides and DNA.
doi:10.1038/35101693
Technology Features
Proteomics technology: Character references p869
Towards an integrated approach.
Potter Wickware and Paul Smaglik
doi:10.1038/35101696
Mass spectroscopy: Mix and match p869
Weighing up the options for proteins.
Potter Wickware and Paul Smaglik
doi:10.1038/35101702
Automation: Multiple choice p871
Industrialization speeds protein discovery.
Potter Wickware and Paul Smaglik
doi:10.1038/35101705
Chips: Alternative approaches p873
Fresh angles for arranging arrays.
Potter Wickware and Paul Smaglik
doi:10.1038/35101708
Software: Setting standards p875
As hardware links up, software diverges.
Potter Wickware and Paul Smaglik
doi:10.1038/35101710
Proteomics product suppliers p877
doi:10.1038/35101714
