Figures and Tables
From the following article:
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
J. Cliff Yoon, Pere Puigserver, Guoxun Chen, Jerry Donovan, Zhidan Wu, James Rhee, Guillaume Adelmant, John Stafford, C. Ronald Kahn, Daryl K. Granner, Christopher B. Newgard and Bruce M. Spiegelman
Nature 413, 131-138(13 September 2001)
doi:10.1038/35093050
Figure 2
PGC-1 gene expression is induced in cultured hepatocytes by treatment with gluconeogenic hormones.
Full size figure and legend (19K)
Figure 3
PGC-1 gene expression is increased in the livers of insulin-deficient animals.
Full size figure and legend (49K)
Figure 4
Adenovirus-mediated expression of PGC-1 induces multiple genes of the gluconeogenic pathway in hepatocytes.
Full size figure and legend (45K)
Figure 5
Expression of PGC-1 enhances glucose production in hepatocytes in the absence of hormonal treatment.
Full size figure and legend (19K)
Figure 6
PGC-1 activates the PEPCK promoter through a functional interaction with HNF-4
.
Figure 7
PGC-1 physically interacts with HNF-4 in cells and in vitro.
